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1. (WO1991006589) NEW ANTI-HIV COMPOUNDS BELONGING TO AURINTRICARBOXYLIC ACID
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/006589 International Application No.: PCT/US1990/006408
Publication Date: 16.05.1991 International Filing Date: 05.11.1990
Chapter 2 Demand Filed: 05.11.1990
IPC:
C07C 65/105 (2006.01) ,C07C 65/11 (2006.01) ,C07C 65/40 (2006.01) ,C07C 309/42 (2006.01) ,C08G 8/08 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
65
Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, -CHO, keto, ether, groups, groups, or groups
01
containing hydroxy or O-metal groups
105
polycyclic
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
65
Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, -CHO, keto, ether, groups, groups, or groups
01
containing hydroxy or O-metal groups
105
polycyclic
11
with carboxyl groups on a condensed ring system containing two rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
65
Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, -CHO, keto, ether, groups, groups, or groups
32
containing keto groups
40
containing singly bound oxygen-containing groups
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
309
Sulfonic acids; Halides, esters, or anhydrides thereof
01
Sulfonic acids
28
having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
41
containing singly-bound oxygen atoms bound to the carbon skeleton
42
having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
C CHEMISTRY; METALLURGY
08
ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
G
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
8
Condensation polymers of aldehydes or ketones with phenols only
04
of aldehydes
08
of formaldehyde, e.g. of formaldehyde formed in situ
Applicants:
THE UNITED STATES OF AMERICA, represented by THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE [US/US]; Washington, DC 20231, US
PURDUE RESEARCH FOUNDATION [US/US]; Office of Technology Transfer 328 Engineering Administration Building West Lafayette, IN 47907, US
Inventors:
HAUGWITZ, Rudiger, D.; US
NARAYANAN, Venkatachala; US
CUSHMAN, Marc; US
Agent:
OLIFF, James, A. ; Oliff & Berridge P.O. Box 19928 Alexandria, VA 22320, US
Priority Data:
431,56803.11.1989US
Title (EN) NEW ANTI-HIV COMPOUNDS BELONGING TO AURINTRICARBOXYLIC ACID
(FR) NOUVEAUX COMPOSES ANTI-HIV APPARTENANT A L'ACIDE AURINTRICARBOXYLIQUE
Abstract:
(EN) The invention relates to the synthesis of compounds with anti-retroviral activity. The synthesis of substantially pure aurintricarboxylic acid monomer and structurally defined polymers, analogs and derivatives thereof, is described. The compounds are shown to have potent anti-retroviral activity, particularly against HIV-1.
(FR) Synthèse de composés présentant une activité antirétrovirale. La synthèse d'un monomère d'acide aurintricarboxylique pur ainsi que de polymères structurellement définis, d'analogues et de dérivés de ceux-ci, est décrite. On a démontré que les composés présentent une activité antirétrovirale puissante, notamment contre le VIH-1.
Designated States: AU, CA, JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1990067282