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1. (WO1991006554) NUCLEOSIDE DERIVATIVES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/006554 International Application No.: PCT/EP1990/001853
Publication Date: 16.05.1991 International Filing Date: 06.11.1990
Chapter 2 Demand Filed: 15.04.1991
IPC:
C07D 405/04 (2006.01) ,C07D 405/14 (2006.01) ,C07H 19/06 (2006.01) ,C07H 19/16 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02
containing two hetero rings
04
directly linked by a ring-member-to-ring- member bond
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
405
Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
14
containing three or more hetero rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19
Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02
sharing nitrogen
04
Heterocyclic radicals containing only nitrogen as ring hetero atom
06
Pyrimidine radicals
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
H
SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19
Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02
sharing nitrogen
04
Heterocyclic radicals containing only nitrogen as ring hetero atom
16
Purine radicals
Applicants:
NYCOMED AS [NO/NO]; Nycoveien 1-2 N-0401 Oslo, NO (AllExceptUS)
KLAVENESS, Jo [NO/NO]; NO (UsOnly)
UNDHEIM, Kjell [NO/NO]; NO (UsOnly)
RISE, Frode [NO/SE]; SE (UsOnly)
HATLELID, Jostein [NO/NO]; NO (UsOnly)
Inventors:
KLAVENESS, Jo; NO
UNDHEIM, Kjell; NO
RISE, Frode; SE
HATLELID, Jostein; NO
Agent:
HOLMES, Michael, John; Frank B. Dehn & Co. Imperial House 15-19 Kingsway London WC2B 6UZ, GB
Priority Data:
8925037.706.11.1989GB
8925039.506.11.1989GB
Title (EN) NUCLEOSIDE DERIVATIVES
(FR) DERIVES DE NUCLEOSIDES
Abstract:
(EN) Compounds of formula (I) wherein Y1 is a hydrogen atom or an acyl or acyloxymethyl group; A and B are respectively a fluorine atom and a hydrogen atom or together represent a carbon-carbon bond; and X is a purine or pyrimidine base or an ester, amide or acyloxyalkyl derivative thereof. The compounds have antiviral activity.
(FR) Composés de formule (I), dans laquelle Y1 représente un atome d'hydrogène ou un groupe acyle ou acyloxyméthyle; A et B représentent respectivement un atome de fluor et un atome d'hydrogène, ou représentent ensemble une liaison carbone-carbone; et X représente une base de purine ou de pyrimidine, ou un dérivé ester, amide ou acyloxyalkyle de celle-ci. Les composés présentent une activité antivirale.
Designated States: AU, CA, FI, JP, NO, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
FI922014NO19921776EP0500610CA2073063AU1990066192