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1. (WO1991006547) INDOLIZIDINE ALKALOIDS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/006547 International Application No.: PCT/GB1990/001655
Publication Date: 16.05.1991 International Filing Date: 29.10.1990
Chapter 2 Demand Filed: 28.05.1991
IPC:
C07D 471/04 (2006.01) ,C07G 5/00 (2006.01) ,C12P 17/18 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
G
COMPOUNDS OF UNKNOWN CONSTITUTION
5
Alkaloids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
17
Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms
18
containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
Applicants:
NOVALAL PLC [GB/GB]; 100 Park Lane Mayfair London W1Y 4AR, GB (AllExceptUS)
BROBY, Haldane, Alexander, Pontoppidan [GB/GB]; GB (UsOnly)
Inventors:
BROBY, Haldane, Alexander, Pontoppidan; GB
Agent:
MICHAEL A. ENSKAT & CO.; 9 Rickmansworth Road Watford Hertfordshire WD1 7HE, GB
Priority Data:
8924292.927.10.1989GB
Title (EN) INDOLIZIDINE ALKALOIDS
(FR) ALCALOIDES D'INDOLIZIDINE
Abstract:
(EN) Alkaloid dimers formed by reacting either Castanospermine or Swainsomine with a compound of formula (1) in the presence of beta cyclo-dextrin glucosyl transferase. The novel dimers are useful as antiviral agents. Pharmaceutical compositions containing alkaloid dimers are also enclosed.
(FR) Dimères d'alcaloïdes formés en faisant réagir soit de la Castanospermine, soit de la Swainsomine, avec un composé de la formule (1) en présence de bêta cyclo-dextrine glucosyle tranférase. Ces nouveaux dimères sont efficaces comme agents anti-viraux. La présente invention décrit aussi des préparations pharmaceutiques à base de ces dimères d'alcaloïdes.
Designated States: AT, AU, BB, BG, BR, CA, CH, DE, DK, ES, FI, GB, HU, JP, KP, KR, LK, LU, MC, MG, MW, NL, NO, RO, SD, SE, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1990066307