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1. (WO1991006304) SYNTHESIS, COMPOSITION AND MEDICAL APPLICATION OF CYCLIC PENTABORATE COMPOUNDS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/006304 International Application No.: PCT/US1990/006331
Publication Date: 16.05.1991 International Filing Date: 31.10.1990
Chapter 2 Demand Filed: 31.05.1991
IPC:
A61K 33/22 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
22
Boron compounds
Applicants:
AMERICAN BIOTECH RESOURCES, INC. [US/US]; 12500 Network Suite 112 San Antonio, TX 78249, US
TEXAS CPR, INC. [US/US]; 12500 Network Suite 112 San Antonio, TX 78249, US
Inventors:
DREESMAN, Gordon, R.; US
BURK, Kenneth, H.; US
CORONEL, Ignacio; MX
GALVAN, Juan, Pablo; MX
RODRIGUEZ, Rafael, A.; MX
Agent:
KAMMERER, Patricia, A.; Arnold, White & Durkee P.O. Box 4433 Houston, TX 77210, US
DOST, Wolfgang ; Galileiplatz 1 D-81679 München, DE
Priority Data:
429,82531.10.1989US
Title (EN) SYNTHESIS, COMPOSITION AND MEDICAL APPLICATION OF CYCLIC PENTABORATE COMPOUNDS
(FR) SYNTHESE, COMPOSITION ET APPLICATION MEDICALE DE COMPOSES DE PENTABORATE CYCLIQUE
Abstract:
(EN) A cyclic pentaborate composition is provided which exhibits immuno-modulatory activity and anti-bacterial in animals including humans. This composition is prepared from a chemical reaction between boric acid and borax (sodium tetra-borate dodecahydrate) in the presence of cytosol fluid obtained from boric acid hypersensitized fungal or microorganism cultures. The cyclic pentaborate compositions of this invention have been useful in enhancing the antibody production in treated animals afflicted with AIDS, pneumonia, osteomyelitis, systemic lupus erythematosus, allergies, asthma, insecticidal intoxication, pre-eclampsia and a variety of other bacterial or viral infectious diseases.
(FR) Composition de pentaborate cyclique présentant une activité immuno-modulatrice et antibactérienne chez l'animal et chez l'homme. On prépare cette composition à partir d'une réaction chimique entre de l'acide borique et du borax (sodium tétra-borate dodécahydrate) en présence de fluide de cytosol obtenu à partir de cultures fongiques ou de microorganismes hypersensibilisés par l'acide borique. Les compositions de pentaborate cyclique sont utiles pour favoriser la production d'anticorps chez des animaux traités atteints du SIDA, de pneumonie, d'ostéomyélite, de lupus érythémateux systémique, d'allergies, de l'asthme, d'intoxication par un insecticide, de pre-éclampsie et d'une variété d'autres maladies infectieuses bactériennes ou virales.
Designated States: AT, AU, BB, BG, BR, CA, CH, DE, DK, ES, FI, GB, HU, JP, KP, KR, LK, LU, MC, MG, MW, NL, NO, RO, SD, SE, SU
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0502978CA2072619AU1991069611