Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1991005873) MIXED IMMUNOGLOBULINS FOR DETECTION OF RHEUMATOID FACTORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/005873 International Application No.: PCT/US1990/005624
Publication Date: 02.05.1991 International Filing Date: 03.10.1990
Chapter 2 Demand Filed: 17.04.1991
IPC:
G01N 33/564 (2006.01) ,G01N 33/58 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
564
for pre-existing immune complex or autoimmune disease
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58
involving labelled substances
Applicants:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1400 Ueberreth Building 405 Hilgard Avenue Los Angeles, CA 90024-1406, US
Inventors:
WEISBART, Richard; US
Agent:
ROWLAND, Bertram, I. ; Cooley, Godward, Castro, Huddleson & Tatum 5 Palo Alto Square, 4th Floor Palo Alto, CA 94306, US
ELLEDGE, Barry, W. ; Cooley, Godward, Castro, Huddleson & Tatum 5 Palo Alto Square, 4th Floor Palo Alto, CA 94306, US
Priority Data:
425,47423.10.1989US
517,24601.05.1990US
Title (EN) MIXED IMMUNOGLOBULINS FOR DETECTION OF RHEUMATOID FACTORS
(FR) IMMUNOGLOBULINES MELANGEES DE DETECTION DE FACTEURS RHUMATOïDES
Abstract:
(EN) Assays are provided for detecting the existence of active rheumatoid arthritis by detecting rheumatoid factor as a blood component which cross-links human IgG with sheep IgG. Particularly, an enzyme labelled assay is provided using biotin-avidin to link the enzyme to the immunoglobulin.
(FR) On a mis au point des analyses permettant de détecter l'existence de polyarthrite rhumatoïde active, par détection du facteur rhumatoïde constituant un composant sanguin réticulant l'IgG humaine avec l'igG du mouton. Notamment, on a mis au point une analyse à marquage enzymatique utilisant la biotine avidine afin de lier l'enzyme à l'immunoglobuline.
Designated States: CA, JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0497886CA2070411