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1. (WO1991005802) OSTEOGENIC DEVICES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/005802 International Application No.: PCT/US1990/005903
Publication Date: 02.05.1991 International Filing Date: 15.10.1990
IPC:
A61C 8/00 (2006.01) ,A61F 2/00 (2006.01) ,A61K 38/00 (2006.01) ,A61L 27/22 (2006.01) ,A61L 27/24 (2006.01) ,A61L 27/34 (2006.01) ,A61L 27/36 (2006.01) ,C07K 14/51 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
C
DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
8
Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
F
FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2
Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
14
Macromolecular materials
22
Polypeptides or derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
14
Macromolecular materials
22
Polypeptides or derivatives thereof
24
Collagen
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
28
Materials for coating prostheses
34
Macromolecular materials
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27
Materials for prostheses or for coating prostheses
36
containing ingredients of undetermined constitution or reaction products thereof
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
475
Growth factors; Growth regulators
51
Bone morphogenic factor; Osteogenin; Osteogenic factor; Bone-inducing factor
Applicants:
CREATIVE BIOMOLECULES, INC. [US/US]; 35 South Street Hopkinton, MA 01748, US
Inventors:
OPPERMANN, Hermann; US
KUBERASAMPATH, Thangavel; US
RUEGER, David, C.; US
OZKAYNAK, Engin; US
PANG, Roy, H., L.; US
Agent:
PITCHER, Edmund, R.; Lahive & Cockfield 60 State Street Boston, MA 02109, US
Priority Data:
422,69917.10.1989US
483,91322.02.1990US
569,92020.08.1990US
Title (EN) OSTEOGENIC DEVICES
(FR) DISPOSITIFS OSTEOGENES
Abstract:
(EN) Disclosed are 1) amino acid sequence data, structural features, and various other data characterizing a human osteogenic protein, OP1, 2) osteogenic devices comprising a heat treated xenogenic bone collagen matrix containing osteogenic protein, 3) methods of producing osteogenic proteins using recombinant DNA technology and 4) use of osteogenic devices to mimic the natural course of endochondral bone formation in mammals.
(FR) L'invention concerne 1) des données de séquences d'acide aminé, des caractéristiques structurelles, ainsi que diverses autres données caractérisant une protéine ostéogène humaine, OP1, 2) des dispositifs ostéogènes comprenant une matrice de collagène d'os xénogène traité thermiquement, contenant une protéine ostéogène, 3) des procédés de production de protéines ostéogènes par génie génétique et 4) l'emploi de dispositifs ostéogènes afin de mimer le cours naturel de la formation d'os cartilagineux chez des mammifères.
Designated States: AU, CA, JP
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0448704CA2042577AU1990066481DK0448704