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1. (WO1991005776) 3-ARYL OXAZOLIDINONES AND THEIR PREPARATION AND USE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/005776 International Application No.: PCT/FR1990/000747
Publication Date: 02.05.1991 International Filing Date: 17.10.1990
IPC:
C07D 263/24 (2006.01) ,C07D 413/12 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
263
Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
02
not condensed with other rings
08
having one double bond between ring members or between a ring member and a non-ring member
16
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
18
Oxygen atoms
20
attached in position 2
24
with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
413
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
Applicants:
DELALANDE S.A. [FR/FR]; 32, rue Henri-Regnault F-92400 Courbevoie, FR
Inventors:
JARREAU, François-Xavier; FR
ROVEI, Vincenzo; FR
KOENIG, Jean-Jacques; FR
SCHOOFS, Alain; FR
Agent:
CABINET MALEMONT; 42, avenue du Président-Wilson F-75116 Paris, FR
Priority Data:
89/1355517.10.1989FR
Title (EN) 3-ARYL OXAZOLIDINONES AND THEIR PREPARATION AND USE
(FR) ARYL-3 OXAZOLIDINONES LEUR PREPARATION ET UTILISATION
Abstract:
(EN) Derivatives of the formula (I) wherein R1 represents H or C1-C4 alkyl; X represents an oxygen atom, a methylene group or a -CH=CH- group; n has a value of 1 or 2 when X is an oxygen atom or a methylene group, and a value of 0 or 1 when X represents the -CH=CH- group; D represents an oxygen atom or a NOR group wherein R=H or C1-C4 alkyl; R3 represents a C1-C4 alkyl group, C3-C7 cycloalkyl, phenyl or benzyl; R2 and R'2 each independently represent a hydrogen atom or a C1-C4 alkyl group, C4-C7 cycloalkyl, phenyl or benzyl; and R'2 and R3 can also together form a -(CH2)3- or -(CH2)4- chain, which are useful as medecines.
(FR) Dérivés répondant à la formule (I), où: R1 représente H ou alkyle en C1-C4; X représente un atome d'oxygène, un groupe méthylène ou un groupe -CH=CH-; n prend la valeur 1 ou 2 quand X est un atome d'oxygène ou un groupe méthylène et la valeur 0 ou 1 quand X représente le groupe -CH=CH-; D représente un atome d'oxygène ou un groupe NOR où R=H ou alkyle en C1-C4; R3 représente un groupe alkyle en C1-C4, cycloalkyle en C3-C7, phényle ou benzyle; R2 et R'2 représentent chacun indépendamment l'un de l'autre, un atome d'hydrogène ou un groupe alkyle en C1-C4, cycloalkyle en C4-C7, phényle ou benzyle; et R'2 et R3 peuvent en outre former ensemble une chaîne -(CH2)3- ou -(CH2)4-, utiles en tant que médicaments.
Designated States: JP, KR
Publication Language: French (FR)
Filing Language: French (FR)
Also published as:
KR1019920701178