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1. (WO1991005757) LIPOXYGENASE INHIBITORS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1991/005757 International Application No.: PCT/US1990/005824
Publication Date: 02.05.1991 International Filing Date: 17.10.1990
Chapter 2 Demand Filed: 03.05.1991
IPC:
C07C 43/23 (2006.01) ,C07C 45/29 (2006.01) ,C07C 47/277 (2006.01) ,C07C 59/64 (2006.01) ,C07C 69/007 (2006.01) ,C07C 69/734 (2006.01) ,C07C 259/06 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
43
Ethers; Compounds having groups, groups or groups
02
Ethers
20
having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
23
containing hydroxy or O-metal groups
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
45
Preparation of compounds having CO groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
27
by oxidation
29
of hydroxy groups
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
47
Compounds having -CHO groups
20
Unsaturated compounds having -CHO groups bound to acyclic carbon atoms
277
containing ether groups, groups, groups, or groups
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
59
Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O-metal, -CHO, keto, ether, groups, groups, or groups
40
Unsaturated compounds
58
containing ether groups, groups, groups, or groups
64
containing six-membered aromatic rings
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
69
Esters of carboxylic acids; Esters of carbonic or haloformic acids
02
Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
04
Formic acid esters
06
of monohydroxylic compounds
07
of unsaturated alcohols
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
69
Esters of carboxylic acids; Esters of carbonic or haloformic acids
66
Esters of carboxylic acids having esterified carboxyl groups bound to acyclic carbon atoms and having any of the groups OH, O-metal, -CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
73
of unsaturated acids
734
Ethers
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
259
Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
04
without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
06
having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
Applicants:
SCHERING CORPORATION [US/US]; 2000 Galloping Hill Road Kenilworth, NJ 07033, US (AllExceptUS)
SHIH, Neng-Yang [US/US]; US (UsOnly)
MANGIARACINA, Pietro [US/US]; US (UsOnly)
Inventors:
SHIH, Neng-Yang; US
MANGIARACINA, Pietro; US
Agent:
ROSEN, Gerald, S. ; Schering-Plough Corporation One Giralda Farms Madison, NJ 07940-1000, US
Priority Data:
424,04419.10.1989US
Title (EN) LIPOXYGENASE INHIBITORS
(FR) INHIBITEURS DE LIPOXYGENASE
Abstract:
(EN) Novel compounds of formula (1) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Also disclosed are pharmaceutical compositions containing compounds of formula (1). Methods of treating allergy, inflammation and hyperproliferative skin diseases with compounds of formula (1) are also disclosed.
(FR) On a mis au point des nouveaux composés de la formule (1), un sel ou un solvate pharmaceutiquement acceptable de celle-ci. On a également mis au point des compositions pharmaceutiques contenant des composés de la formule (1), ainsi que des procédés de traitements d'allergies d'inflammations et de dermatoses hyperprolifératives à l'aide des composés de la formule (1).
Designated States: AU, BB, BG, BR, CA, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, RO, SD, SU, US
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, GR, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0495917US5563292JPH05503923AU1990067272