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1. WO1991000742 - SOLUBLE HUMAN B-CELL INTERLEUKIN-1 RECEPTOR

Publication Number WO/1991/000742
Publication Date 24.01.1991
International Application No. PCT/US1990/003556
International Filing Date 28.06.1990
Chapter 2 Demand Filed 07.01.1991
IPC
C07K 14/715 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
715for cytokines; for lymphokines; for interferons
E02F 9/22 2006.01
EFIXED CONSTRUCTIONS
02HYDRAULIC ENGINEERING; FOUNDATIONS; SOIL-SHIFTING
FDREDGING; SOIL-SHIFTING
9Component parts of dredgers or soil-shifting machines, not restricted to one of the kinds covered by groups E02F3/-E02F7/160
20Drives; Control devices
22Hydraulic or pneumatic drives
CPC
C07K 14/7155
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
715for cytokines; for lymphokines; for interferons
7155for interleukins [IL]
E02F 9/2292
EFIXED CONSTRUCTIONS
02HYDRAULIC ENGINEERING; FOUNDATIONS; SOIL SHIFTING
FDREDGING; SOIL-SHIFTING
9Component parts of dredgers or soil-shifting machines, not restricted to one of the kinds covered by groups E02F3/00 - E02F7/00
20Drives; Control devices
22Hydraulic or pneumatic drives
2278Hydraulic circuits
2292Systems with two or more pumps
Applicants
  • E.I. DU PONT DE NEMOURS AND COMPANY [US/US]; 1007 Market Street Wilmington, DE 19898, US
Inventors
  • GIRI, Judith, Goldstein; US
  • HORUK, Richard; US
Agents
  • HORN, Margaret, A. ; E.I. du Pont de Nemours and Company Legal Department 1007 Market Street Wilmington, DE 19898, US
Priority Data
376,95607.07.1989US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SOLUBLE HUMAN B-CELL INTERLEUKIN-1 RECEPTOR
(FR) RECEPTEUR DE L'INTERLEUKIN-1 SOLUBLE ISOLE DES CELLULES B HUMAINES
Abstract
(EN)
A soluble, membrane-free and detergent-free interleukin-1 (IL-1) receptor isolated from a human B-cell line is described. The soluble human B-cell IL-1 receptor has an apparent molecular size of about 40 kDa and exhibits at least about a 10-fold greater binding affinity for IL-1$g(b) than IL-1$g(a).
(FR)
L'invention concerne un récepteur de l'interleukin-1 (IL-1) soluble, sans membrane et sans détergent, lequel récepteur a été isolé d'une ligne de cellule B humaine. Le récepteur soluble IL-1 des cellules B humaines possède une taille moléculaire apparente d'environ 40 kDa et présente au moins environ une affinité de liaison pour IL-1$g(b) 10 fois supérieure à celle pour IL-1$g(a).
Also published as
Latest bibliographic data on file with the International Bureau