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1. WO1991000351 - FUNGAL STRESS PROTEINS

Publication Number WO/1991/000351
Publication Date 10.01.1991
International Application No. PCT/GB1990/001021
International Filing Date 02.07.1990
IPC
A61K 38/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/40 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
37from fungi
39from yeasts
40from Candida
C07K 16/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
14against material from fungi, algae or lichens
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
C07K 14/40
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
37from fungi
39from yeasts
40from Candida
C07K 16/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
14against material from fungi, algea or lichens
C07K 2317/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
30characterized by aspects of specificity or valency
34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Y10S 435/921
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
435Chemistry: molecular biology and microbiology
8215Microorganisms
911using fungi
921Candida
Y10S 435/922
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
435Chemistry: molecular biology and microbiology
8215Microorganisms
911using fungi
921Candida
922Candida albicans
Applicants
  • BURNIE, James, Peter [GB/GB]; GB
  • MATTHEWS, Ruth, Christine [GB/GB]; GB
Inventors
  • BURNIE, James, Peter; GB
  • MATTHEWS, Ruth, Christine; GB
Agents
  • HALLYBONE, Huw, George; Carpmaels & Ransford 43 Bloomsbury Square London WC1A 2RA, GB
Priority Data
8915019.730.06.1989GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) FUNGAL STRESS PROTEINS
(FR) PROTEINES DE STRESS FONGIQUES
Abstract
(EN)
A polypeptide sequence from $i(Candida albicans) is described which has significant sequence homology with known stress proteins from other organisms, particularly the heat shock protein hsp 90 of $i(Sacchromyces cerevisiae). Corresponding DNA sequences are also described, together with antibodies raised against fragments of the sequence. The polypeptide and DNA sequences and antibodies provide separate means for the diagnosis and/or treatment of fungal, particularly Candida, infections.
(FR)
On décrit une séquence de polypeptides provenant de $i(Candida albicans) qui présente une homologie de séquences significative par rapport à des protéines de stress connues provenant d'autres organismes, en particulier la protéine de choc provoqué par la chaleur hsp 90 de $i(Sacchromyces cervisiae). On décrit également des séquences d'ADN correspondantes, ainsi que des anticorps dressés contre des fragments de la séquence. Les séquences de polypeptide et d'ADN ainsi que les anticorps constituent des moyens séparés pour le diagnostic et/ou le traitement d'infections fongiques, en particulier des infections Candida.
Also published as
GB9102985.0
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