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1. WO1991000104 - PRODUCTION OF VIRUS AND PURIFICATION OF VIRAL ENVELOPE PROTEINS FOR VACCINE USE

Publication Number WO/1991/000104
Publication Date 10.01.1991
International Application No. PCT/CA1990/000205
International Filing Date 28.06.1990
Chapter 2 Demand Filed 28.01.1991
IPC
C07K 14/115 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
115Paramyxoviridae, e.g. parainfluenza virus
C07K 14/135 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
115Paramyxoviridae, e.g. parainfluenza virus
135Respiratory syncytial virus
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
CPC
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C12N 2760/18522
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2760ssRNA Viruses negative-sense
00011ssRNA Viruses negative-sense
18011Paramyxoviridae
18511Pneumovirus, e.g. human respiratory syncytial virus
18522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
C12N 2760/18622
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
2760ssRNA Viruses negative-sense
00011ssRNA Viruses negative-sense
18011Paramyxoviridae
18611Respirovirus, e.g. Bovine, human parainfluenza 1,3
18622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applicants
  • CONNAUGHT LABORATORIES LIMITED [CA/CA]; 1755 Steeles Avenue West Willowdale, Ontario M2R 3T4, CA (AllExceptUS)
  • EWASYSHYN, Mary, Elizabeth [CA/CA]; CA (UsOnly)
  • CAPLAN, Barry, Ian [CA/CA]; CA (UsOnly)
  • BONNEAU, Anne-Marie [CA/CA]; CA (UsOnly)
  • KLEIN, Michel, Henri [CA/CA]; CA (UsOnly)
Inventors
  • EWASYSHYN, Mary, Elizabeth; CA
  • CAPLAN, Barry, Ian; CA
  • BONNEAU, Anne-Marie; CA
  • KLEIN, Michel, Henri; CA
Agents
  • STEWART, Michael, I.; Sim & McBurney 330 University Avenue Suite 701 Toronto, Ontario M5G 1R7, CA
Priority Data
8914968.629.06.1989GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PRODUCTION OF VIRUS AND PURIFICATION OF VIRAL ENVELOPE PROTEINS FOR VACCINE USE
(FR) PRODUCTION DE VIRUS ET PURIFICATION DE PROTEINES D'ENVELOPPES VIRALES POUR VACCINS
Abstract
(EN)
Immunogenic envelope glycoproteins are produced from enveloped virus, such as of the paramyxoviridae family, particularly PIV-3 and RSV, by culturing the virus in the substantial absence of exogenous serum proteins, isolating the virus from the tissue culture, solubilizing the envelope glycoproteins and isolating the solubilized envelope glycoproteins by chromatography.
(FR)
Des glycoprotéines d'enveloppes immunogènes sont produites à partir de virus enveloppés, tels que les virus de la famille des paramyxoviridae, en particulier le PIV-3 et le RSV, au moyen d'un procédé qui consiste à cultiver le virus en l'absence de protéines sériques exogènes, à isoler le virus de la culture tissulaire, à solubiliser les glycoprotéines d'enveloppes et à isoler par chromatographie les glycoprotéines d'enveloppes solubilisées.
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