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1. WO1991000086 - METHOD AND DEVICE FOR DIRECT PRODUCTION OF NANOCAPSULES

Publication Number WO/1991/000086
Publication Date 10.01.1991
International Application No. PCT/CH1990/000162
International Filing Date 04.07.1990
IPC
A61K 9/127 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
CPC
A61K 9/1277
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
127Liposomes
1277Processes for preparing; Proliposomes
Applicants
  • PATRINOVE [FR/FR]; 39, rue Lt.-Col.-Prévost F-69006 Lyon, FR (AllExceptUS)
  • GUTIERREZ, Gilles [FR/FR]; FR (UsOnly)
Inventors
  • GUTIERREZ, Gilles; FR
Agents
  • DEBIOPHARM S.A.; Case postale 446 CH-1001 Lausanne, CH
Priority Data
89/0927505.07.1989FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) METHOD AND DEVICE FOR DIRECT PRODUCTION OF NANOCAPSULES
(FR) PROCEDE ET DISPOSITIF DE PRODUCTION DIRECTE DE NANOCAPSULES
Abstract
(EN)
The method consists of obtaining a preparation liquid by mixing at least one amphiphilic compound and one aqueous medium with an active substance which is soluble or dispersible in the amphiphilic compound or the aqueous medium, setting in motion the preparation liquid and alternately pressurizing and depressurizing the moving preparation liquid. Applications in the preparation of liposomes.
(FR)
Le procédé consiste à obtenir un liquide de préparation par mélange d'au moins un composé amphiphile, d'un milieu aqueux et de la substance active, soluble ou dispersable dans le composé amphiphile ou le milieu aqueux, à mettre en mouvement le liquide de préparation puis à soumettre le liquide de préparation en mouvement à une alternance de surpressions et de dépressions. Application à la préparation de liposomes.
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