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Machine translation
1. (WO1990015878) IMMUNOACTIVE PEPTIDES AND ANTIBODIES AND THEIR USE IN ANTI-ALLERGY TREATMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1990/015878 International Application No.: PCT/GB1990/000926
Publication Date: 27.12.1990 International Filing Date: 15.06.1990
Chapter 2 Demand Filed: 11.01.1991
IPC:
A61K 38/00 (2006.01) ,A61K 39/00 (2006.01) ,C07K 16/06 (2006.01) ,C07K 16/42 (2006.01)
Applicants: STANWORTH, Denis, Raymond[GB/GB]; GB (UsOnly)
LEWIN, Ian, Victor[GB/GB]; GB (UsOnly)
NAYYAR, Sarita[GB/GB]; GB (UsOnly)
JONES, Valerie[GB/GB]; GB (UsOnly)
NATIONAL RESEARCH DEVELOPMENT CORPORATION[GB/GB]; 101 Newington Causeway London SE1 6BU, GB (AllExceptUS)
Inventors: STANWORTH, Denis, Raymond; GB
LEWIN, Ian, Victor; GB
NAYYAR, Sarita; GB
JONES, Valerie; GB
Agent: PERCY, Richard, Keith; Patent Department National Research Development Corporation 101 Newington Causeway London SE1 6BU, GB
Priority Data:
8913737.615.06.1989GB
Title (EN) IMMUNOACTIVE PEPTIDES AND ANTIBODIES AND THEIR USE IN ANTI-ALLERGY TREATMENT
(FR) PEPTIDES ET ANTICORPS IMMUNOACTIFS ET LEUR UTILISATION DANS LES TRAITEMENTS ANTI-ALLERGIQUES
Abstract:
(EN) An immunogen comprising a residue of a histamine-releasing peptide comprising a cationic N-terminal head and a hydrophobic C-terminal tail, together with a residue capable of eliciting antibodies against said peptide whilst inhibiting histamine release by said peptide is useful in anti-allergy treatment. Preferably the histamine-releasing peptide is of formula: Lys-Thr-Lys-Gly-Ser-Gly-Phe-Phe-Val-Phe, optionally amidated at the C terminal. Antibodies to the histamine-releasing peptide are useful for passive immunisation.
(FR) Un immunogène comprenant un résidu d'un peptide libérateur d'histamine comprenant une tête cationique à terminaison M et une queue hydrophobe à terminaison C, associé à un résidu capable de faire agir les anticorps contre ledit peptide tout en inhibant la libération d'histamine par ledit peptide est utile dans le traitement anti-allergique. De préférence, le peptide libérateur d'histamine correspond à la formule: Lys-Thr-Lys-Gly-Ser-Gly-Phe-Phe-Val-Phe, amidé ou non à la terminaison C. Les anticorps au peptide libérant de l'histamine sont utiles pour l'immunisation passive.
Designated States: AU, CA, FI, JP, KR, NO, US
European Patent Office (EPO) (AT, BE, CH, DE, DK, ES, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)