WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1990015045) OXIDATIVE PREPARATION OF A-NOR-17 BETA-CARBOXY-3,5-SECOANDROSTAN-5-ONE-3 OIC ACID
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1990/015045    International Application No.:    PCT/US1990/002622
Publication Date: 13.12.1990 International Filing Date: 15.05.1990
Chapter 2 Demand Filed:    12.11.1990    
IPC:
C07C 62/24 (2006.01), C07C 62/26 (2006.01), C07J 71/00 (2006.01), C07J 73/00 (2006.01)
Applicants: THE UPJOHN COMPANY [US/US]; 301 Henrietta Street, Kalamazoo, MI 49001 (US) (For All Designated States Except US).
HERRINTON, Paul, Matthew [US/US]; (US) (For US Only)
Inventors: HERRINTON, Paul, Matthew; (US)
Agent: STEIN, Bruce; Corporate Patents & Trademarks, The Upjohn Company, Kalamazoo, MI 49001 (US).
PERRY, Robert, E.; Gill Jennings & Every, 53-64 Chancery Lane, London WC2A 1HN (GB)
Priority Data:
358,800 30.05.1989 US
462,417 09.01.1990 US
Title (EN) OXIDATIVE PREPARATION OF A-NOR-17 BETA-CARBOXY-3,5-SECOANDROSTAN-5-ONE-3 OIC ACID
(FR) PREPARATION PAR OXYDATION DE L'ACIDE A-NOR-17 BETA-CARBOXY-3,5-SECOANDROSTAN-5-ONE-3 OIQUE
Abstract: front page image
(EN)The present invention is an oxidative process for the conversion of 21-unsaturated progesterones (I) to the corresponding 3,5-secoandrost-5-one-3,17$g(b)-dioic acids (II) by use of either ozone or an oxidizing agent, which are useful intermediates in the production of $g(D)5-4-aza-17-carbonyl steroids (III) which are useful in production of 5$g(a)-4-aza amide (IV) pharmaceuticals. Also disclosed are the novel 21-unsaturated progesterones (I-C) and 3,5-secoandrost-5-one-3,17$g(b)-dioic acids (II-C).
(FR)L'invention concerne un procédé d'oxydation permettant de transformer des progestérones 21-non saturées (I) en des acides 3,5-secoandrost-5-one-3,17$g(b)-dioïques homologues (II) en utilisant soit de l'ozone soit un agent d'oxydation, qui sont des intermédiaires utiles à la production de stéroïdes $g(D)5-4-aza-17-carbonyle stéroïdes (III) lesquels sont utiles à la production de produits pharmaceutiques 5$g(a)-4-aza amides (IV). L'invention porte également sur des progestérones 21-non saturées (I-C) et les acides 3,5-secoandrost-5-one-3,17$g(b)-dioïques (II-C).
Designated States: AU, BB, BG, BR, CA, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, RO, SD, SU, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)