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Machine translation
1. (WO1990014822) STEROID MODIFIED OLIGONUCLEOTIDES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1990/014822    International Application No.:    PCT/US1990/003204
Publication Date: 13.12.1990 International Filing Date: 06.06.1990
IPC:
C07H 21/00 (2006.01), C07J 51/00 (2006.01)
Applicants: NORTHWESTERN UNIVERSITY [US/US]; 633 Clark Street, Evanston, IL 60208 (US) (For All Designated States Except US).
LETSINGER, Robert, L. [US/US]; (US) (For US Only)
Inventors: LETSINGER, Robert, L.; (US)
Agent: KOHN, Kenneth, I.; Tilton, Fallon, Lungmus & Chestnut, P.O. Box 4390, Troy, MI 48099 (US)
Priority Data:
362,200 06.06.1989 US
Title (EN) STEROID MODIFIED OLIGONUCLEOTIDES
(FR) OLIGONUCLEOTIDES MODIFIES PAR DES STEROÏDES
Abstract: front page image
(EN)Oligonucleotides modified at their backbones by the attachment of at least one steroid are described. The modified oligonucleotides anchor in the cell membrane to serve as a probe and to provide therapeutic activity.
(FR)L'invention concerne des oligonucléotides modifiés au niveau de leurs squelettes par la fixation d'au moins un stéroïde. Les oligonucléotides modifiés s'ancrent dans la membrane cellulaire afin de servir de sonde et d'exercer une activité thérapeutique.
Designated States: AU, CA, JP, KR, US.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, IT, LU, NL, SE).
Publication Language: English (EN)
Filing Language: English (EN)