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1. WO1990014357 - HER2 EXTRACELLULAR DOMAIN

Publication Number WO/1990/014357
Publication Date 29.11.1990
International Application No. PCT/US1990/002697
International Filing Date 18.05.1990
Chapter 2 Demand Filed 18.12.1990
IPC
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 14/71 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
71for growth factors; for growth regulators
CPC
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
C07K 14/71
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
71for growth factors; for growth regulators
Applicants
  • GENENTECH, INC. [US]/[US]
Inventors
  • HUDZIAK, Robert, Michael
  • SHEPARD, H., Michael
  • ULLRICH, Axel
Agents
  • GREENBLUM, Neil, F.
Priority Data
354,31919.05.1989US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HER2 EXTRACELLULAR DOMAIN
(FR) DOMAINE EXTRACELLULAIRE DE HER2
Abstract
(EN)
An extracellular portion of the HER2 molecule, essentially free of transmembrane and cytoplasmic portions, which is antigenic in animals. Isolated DNA encoding the extracellular portion; an expression vector containing the isolated DNA; and a cell containing the expression vector. A process for producing the extracellular domain. A vaccine containing the extracellular domain.
(FR)
L'invention concerne une partie extracellulaire de la molécule HER2, essentiellement exempte de la portion transmembranaire et de la portion cytoplasmique, laquelle est un antigénique chez les animaux. L'invention concerne également un ADN isolé codant la portion extracellulaire, un vecteur d'expression contenant l'ADN isolé, et une cellule contenant le vecteur d'expression. L'invention concerne aussi un procédé de production du domaine extracellulaire ainsi qu'un vaccin contenant le domaine extracellulaire.
Also published as
Latest bibliographic data on file with the International Bureau