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1. WO1990014352 - 2-HALO-9-(2-DEOXY-2-FLUORO-B-D-ARABINOFURANOSYL) ADENINE NUCLEOSIDE DERIVATIVES

Publication Number WO/1990/014352
Publication Date 29.11.1990
International Application No. PCT/US1990/002927
International Filing Date 23.05.1990
Chapter 2 Demand Filed 13.11.1990
IPC
C07H 19/16 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
16Purine radicals
CPC
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07H 19/16
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides ; Anhydro-derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
16Purine radicals
Applicants
  • SOUTHERN RESEARCH INSTITUTE [US]/[US]
Inventors
  • MONTGOMERY, John, A.
  • SECRIST, John, A., III
Agents
  • BERDO, Robert, H.
Priority Data
355,35823.05.1989US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) 2-HALO-9-(2-DEOXY-2-FLUORO-B-D-ARABINOFURANOSYL) ADENINE NUCLEOSIDE DERIVATIVES
(FR) DERIVES DE NUCLEOSIDES DE 2-HALO-9(2-DESOXY-2-FLUORO-B-D-ARABINOFURANOSYLE) ADENINE
Abstract
(EN)
There are disclosed nucleosides having formula (I), wherein Z is F, Cl or Br and R is H or aryl. These compounds have anticancer activity.
(FR)
l'invention concerne des nucléosides ayant la forme (I) dans laquelle Z représente F, Cl ou Br et R représente H ou aryle. Ces composés présentent une activité anticancéreuse.
Also published as
Latest bibliographic data on file with the International Bureau