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1. WO1990013820 - DETECTION OF APPENDICITIS BY MEASUREMENT OF UROERYTHRIN

Publication Number WO/1990/013820
Publication Date 15.11.1990
International Application No. PCT/US1990/002394
International Filing Date 30.04.1990
IPC
G01N 33/72 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
72involving blood pigments, e.g. hemoglobin, bilirubin
CPC
G01N 33/72
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
72involving blood pigments, e.g. haemoglobin, bilirubin ; or other porphyrins; involving occult blood
Y10T 436/146666
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
436Chemistry: analytical and immunological testing
14Heterocyclic carbon compound [i.e. , O, S, N, Se, Te, as only ring hetero atom]
145555Hetero-N
146666Bile pigment
Y10T 436/24
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
436Chemistry: analytical and immunological testing
24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Applicants
  • BAR-OR, David [IS]/[US]
  • GREISMAN, Stewart, L. [US]/[US]
  • KASTENDIECK, Jon, G. [US]/[US]
Inventors
  • BAR-OR, David
  • GREISMAN, Stewart, L.
  • KASTENDIECK, Jon, G.
Agents
  • FIELDS, Gary, D.
Priority Data
351,19004.05.1989US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DETECTION OF APPENDICITIS BY MEASUREMENT OF UROERYTHRIN
(FR) DETECTION DE L'APPENDICITE PAR MESURE DE L'URO-ERYTHRINE
Abstract
(EN)
Appendicitis can be detected by determining a threshold presence of the urinary pigment uroerythrin, in the urine of persons suspected of having appendicitis. The threshold presence of uroerythrin can be determined by precipitation of a sediment having a pink to red color. Additional qualitative, semiquantitative, or quantitative methods including HPLC (high pressure liquid chromatography), TLC (thin layer chromatography), radioimmunoassay, colorimetric tests, NMR (nuclear magnetic resonance), mass spectrometry, electrophoresis, monoclonal antibody tests, and other enzymatic tests may also be employed to measure uroerythrin levels.
(FR)
On peut détecter l'appendicite en déterminant une présence de seuil du pigment urinaire uro-érythrine, dans l'urine de personnes dont on suppose qu'elles ont l'appendicite. On peut déterminer la présence de seuils d'uro-erythrine par précipitation d'un sédiment ayant une couleur rose à rouge. On peut utiliser des procédés additionnels qualitatifs, semi-quantitatifs, ou quantitatifs, parmi lesquels CLHP (chromatographie liquide à haute pression), CCM (chromatographie en couche mince), la radioimmunoanalyse, des tests colorimétriques, RNM (résonance magnétique nucléaire), la spectrométrie de masse, l'électrophorèse, des tests d'anticorps monoclonaux, ainsi que d'autres tests enzymatiques, afin de mesurer les niveaux d'uro-érythrine.
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