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1. WO1990013297 - 5-AMINOCARBONYL-5H-DIBENZO[a,d]CYCLOHEPTEN-5,10-IMINES FOR TREATMENT OF EPILEPSY AND COCAINE ADDICTION

Publication Number WO/1990/013297
Publication Date 15.11.1990
International Application No. PCT/US1990/001502
International Filing Date 23.03.1990
Chapter 2 Demand Filed 23.03.1990
IPC
C07D 451/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
451Heterocyclic compounds containing 8-azabicyclo octane, 9-azabicyclo nonane, or 3-oxa-9-azatricyclo nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
02containing not further condensed 8-azabicyclo octane or 3-oxa-9-azatricyclo nonane ring systems, e.g. tropane; Cyclic acetals thereof
C07D 471/20 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
12in which the condensed system contains three hetero rings
20Spiro-condensed systems
CPC
C07D 451/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
451Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
Applicants
  • THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, U.S. DEPARTMENT OF COMMERCE [US]/[US]
Inventors
  • MONN, James, A.
  • THURKAUF, Andrew
  • YAMAGUCHI, Shunichi
  • ROGAWSKI, Michael, A.
  • RICE, Kenneth, C.
  • MATTSON, Mariena, V.
  • JACOBSON, Arthur, E.
Agents
  • HOLMAN, John, Clarke
Priority Data
349,18709.05.1989US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) 5-AMINOCARBONYL-5H-DIBENZO[a,d]CYCLOHEPTEN-5,10-IMINES FOR TREATMENT OF EPILEPSY AND COCAINE ADDICTION
(FR) 5-AMINOCARBONYLE-5H-DIBENZO[a,d]CYCLOHEPTENE-5,10-IMINES POUR LE TRAITEMENT DE L'EPILEPSIE ET DE LA COCAINOMANIE
Abstract
(EN)
This invention is in the field of clinical neurology and relates specifically to compounds, compositions and methods for treatment of patients with generalized epilepsy or partial (symptomatic) epilepsy using compounds of formula (I). This invention also relates to compounds, compositions and methods of treatment for drug craving in patients addicted to cocaine.
(FR)
La présente invention, du domaine de la neurologie clinique, a trait en particulier aux composés, compositions et méthodes pour le traitement des patients souffrant d'épilepsie généralisée ou partielle (symptomatique) à l'aide des composés de la formule (I). Cette invention concerne aussi les composés, compositions et méthodes pour le traitement des patients cocaïnomanes en état de manque.
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