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1. (WO1990009443) ANIMAL MODEL FOR BENIGN PROSTATIC DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1990/009443    International Application No.:    PCT/US1990/000926
Publication Date: 23.08.1990 International Filing Date: 16.02.1990
Chapter 2 Demand Filed:    12.09.1990    
IPC:
C07K 14/50 (2006.01), C12N 15/85 (2006.01)
Applicants: PRESIDENT AND FELLOWS OF HARVARD COLLEGE [US/US]; 17 Quincy Street, Cambridge, MA 02139 (US)
Inventors: LEDER, Philip; (US).
MULLER, William, J.; (US)
Agent: CLARK, Paul, T.; Fish & Richardson, One Financial Center, Suite 2500, Boston, MA 02111-2658 (US)
Priority Data:
312,641 17.02.1989 US
Title (EN) ANIMAL MODEL FOR BENIGN PROSTATIC DISEASE
(FR) MODELE ANIMAL DE MALADIES PROSTATIQUES BENIGNES
Abstract: front page image
(EN)A male transgenic non human vertebrate animal containing germ cells and somatic cells which contain a recombinant gene which is substantially homologous with a vertebrate gene in the $i(int)-2/$i(FGF) family which is capable of promoting benign prostatic hyperplasia or hypertrophy in said transgenic vertebrate, said gene being introduced into the animal, or an ancestor of the animal, at an embryonic stage.
(FR)Un animal vertébré mâle transgénique non humain présente des cellules reproductives et des cellules somatiques qui contiennent un gène recombinant essentiellement homologue d'un gène de vertébrés de la famille $i(int)-2/$i(FGF), capable de promouvoir une hyperplasie ou une hypertrophie prostatique bénigne dudit vertébré transgénique. Ce gène est introduit dans l'animal, ou dans un ancêtre de l'animal, à un stade embryonnaire.
Designated States: AU, BB, BG, BR, CA, DK, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, RO, SD, SU.
European Patent Office (AT, BE, CH, DE, DK, ES, FR, GB, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)