WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1990003163) COMPOSITION AND METHOD FOR ENHANCING PERMEABILITY OF TOPICAL DRUGS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1990/003163    International Application No.:    PCT/US1989/003677
Publication Date: 05.04.1990 International Filing Date: 29.08.1989
Chapter 2 Demand Filed:    09.04.1990    
IPC:
A61K 47/12 (2006.01), A61K 47/18 (2006.01)
Applicants: UNIVERSITY OF FLORIDA [US/US]; 207 Tigert Hall, Gainesville, FL 32611 (US)
Inventors: BODOR, Nicholas, S.; (US).
LOFTSSON, Thorsteinn; (IS)
Agent: CLARKE, Dennis, P.; Kerkam, Stowell, Kondracki & Clarke, 6404 R Seven Corners Place, Falls Church, VA 22044-2010 (US)
Priority Data:
247,532 22.09.1988 US
Title (EN) COMPOSITION AND METHOD FOR ENHANCING PERMEABILITY OF TOPICAL DRUGS
(FR) COMPOSITION ET PROCEDE PERMETTANT D'AMELIORER LA PERMEABILITE DE MEDICAMENTS TOPIQUES
Abstract: front page image
(EN)A composition and method for enhancing permeability of topical drugs wherein the agent which enhances the permeability of the drug is selected from the group consisting of (1) a choline ester having the formula: [CH¿3?(CH¿2?)¿n?-COOCH¿2?CH¿2?N?+¿(CH¿3?)¿3?]X?-¿ or [CH¿3?(CH¿2?)¿m?CH=CH(CH¿2?)¿n?-COOCH¿2?CH¿2?N?+¿(CH¿3?)¿3?]X?-¿, wherein m and n are integers in the range of from 0 to 30 and X?-¿ is a pharmaceutically acceptable anion and (2) a mixture of the choline ester and an acid having the formula: CH¿3?(CH¿2?)¿n?-COOH or CH¿3?(CH¿2?)¿m?CH=CH(CH¿2?)¿n?-COOH or a pharmaceutically acceptable salt thereof.
(FR)Dans la composition et le procédé décrits, qui permettent d'améliorer la perméabilité de médicaments topiques, l'agent améliorant la perméabilité de médicaments est choisi dans le groupe composé de (1) un ester de choline représenté par la formule: [CH¿3?(CH¿2?)¿n?-COOCH¿2?CH¿2?N?+¿(CH¿3?)¿3?]X?-¿ ou [CH¿3?(CH¿2?)¿m?CH=CH(CH¿2?)¿n?-COOCH¿2?CH¿2?N?+¿(CH¿3?)¿3?]X?-¿, où m et n représentent des nombres entiers compris entre 0 et 30 et X?-¿ représente un anion pharmaceutiquement acceptable; et (2) un mélange de l'ester de choline et d'un acide représenté par la formule CH¿3?(CH¿2?)¿n?-COOH ou CH¿3?(CH¿2?)¿m?CH=CH(CH¿2?)¿n?-COOH; ou d'un sel pharmaceutiquement acceptable de ces composés.
Designated States: JP.
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE).
Publication Language: English (EN)
Filing Language: English (EN)