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1. WO1990002938 - DISPOSABLE SENSING DEVICE FOR REAL TIME FLUID ANALYSIS

Publication Number WO/1990/002938
Publication Date 22.03.1990
International Application No. PCT/US1989/003965
International Filing Date 15.09.1989
Chapter 2 Demand Filed 13.04.1990
IPC
G01N 27/28 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
G01N 33/487 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
487of liquid biological material
CPC
B01L 2300/0672
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
06Auxiliary integrated devices, integrated components
0672Integrated piercing tool
B01L 2300/087
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0861Configuration of multiple channels and/or chambers in a single devices
087Multiple sequential chambers
B01L 2400/0481
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
04Moving fluids with specific forces or mechanical means
0475specific mechanical means and fluid pressure
0481squeezing of channels or chambers
B01L 2400/0683
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2400Moving or stopping fluids
06Valves, specific forms thereof
0677phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
0683mechanically breaking a wall or membrane within a channel or chamber
B01L 3/502707
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502707characterised by the manufacture of the container or its components
B01L 3/502715
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502715characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
Applicants
  • I-STAT CORPORATION [US]/[US]
Inventors
  • LAUKS, Imants, R.
  • WIECK, Henry, J.
  • ZELIN, Michael, P.
  • BLYSKAL, Philip
Agents
  • MISROCK, S., Leslie
Priority Data
245,10215.09.1988US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DISPOSABLE SENSING DEVICE FOR REAL TIME FLUID ANALYSIS
(FR) DISPOSITIF DE DETECTION JETABLE POUR L'ANALYSE DE FLUIDES EN TEMPS REEL
Abstract
(EN)
A system comprising a disposable device (10) and hand held reader (150) can perform a variety of electrochemical measurements on blood or other fluids. In operation, a fluid sample is drawn into the disposable device through an orifice (108) by capillary action. The orifice is sealed off and the disposable device is inserted into the reader. The reader which controls the test sequence and flow of fluid causes a calibrant pouch (60) located inside the device to be pierced, releasing the calibrant fluid to flow across the sensor arrays (66) to perform calibration. Next an air bladder located in the device is depressed, forcing the sample across the sensors where the measurements are performed and read by the reader (150) which performs the calibrations. Once the measurements are made, the device can be withdrawn from the reader (150) and discarded.
(FR)
Un système comprenant un dispositif jetable (10) et un lecteur tenu dans la main (150) peut effectuer une variété de mesures électrochimiques sur du sang ou d'autres fluides. Le fonctionnement du système consiste à aspirer un échantillon de fluide dans le dispositif jetable au travers d'un orifice (108) par action capillaire. L'orifice est fermé hermétiquement et le dispositif jetable est introduit dans le lecteur. Le lecteur, qui commande la séquence de test et l'écoulement de fluide, provoque le perçage d'une poche (60) placée à l'intérieur du dispositif, ce qui libère un fluide calibreur contenu dans la poche, ce fluide calibreur s'écoulant dans les réseaux de capteurs (66) pour effectuer un calibrage. Ensuite, une vessie d'air placée dans le dispositif est décompressée, ce qui a pour résultat de forcer l'échantillon à passer au travers des capteurs où les mesures sont effectuées et lues par le lecteur (150) qui effectue les calibrages. Après avoir effectué les mesures, le dispositif peut être retiré du lecteur (150), puis jeté.
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