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Machine translation
1. (WO1990002800) NEW DERIVATIVES OF HUMAN/BOVINE BASIC FIBROBLAST GROWTH FACTOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1990/002800    International Application No.:    PCT/EP1989/001075
Publication Date: 22.03.1990 International Filing Date: 15.09.1989
IPC:
A61K 38/00 (2006.01), C07K 14/50 (2006.01)
Applicants: FARMITALIA CARLO ERBA S.R.L. [IT/IT]; Via Carlo Imbonati, 24, I-20159 Milan (IT) (For All Designated States Except US).
BERGONZONI, Laura [IT/IT]; (IT) (For US Only).
ISACCHI, Antonella [IT/IT]; (IT) (For US Only).
SARMIENTOS, Paolo [IT/IT]; (IT) (For US Only).
CAUET, Gilles [FR/IT]; (IT) (For US Only)
Inventors: BERGONZONI, Laura; (IT).
ISACCHI, Antonella; (IT).
SARMIENTOS, Paolo; (IT).
CAUET, Gilles; (IT)
Agent: KOLB, Helga; Arabellastrasse 4, D-8000 Münich 81 (DE)
Priority Data:
8821795.5 16.09.1988 GB
Title (EN) NEW DERIVATIVES OF HUMAN/BOVINE BASIC FIBROBLAST GROWTH FACTOR
(FR) NOUVEAUX DERIVES DU FACTEUR DE CROISSANCE DE FIBROBLASTE HUMAIN/BOVIN
Abstract: front page image
(EN)The present invention relates to the production, by recombinant DNA techniques, of derivatives of basic fibroblast growth factor (bFGF). These derivatives of bFGF can act as antagonists and/or superagonists of the wild type molecule in the angiogenic process. These derivatives, as well as wild type bFGF, may be prepared by the use of strains or $i(E. coli) which have been transformed with plasmids carrying nucleotide sequence coding for human and bovine bFGF and their derivatives.
(FR)Cette invention concerne la production, par des techniques de recombinaison d'ADN, de dérivés du facteur de croissance de fibroblaste basique (bFGF). Ces dérivés de bFGF peuvent agir comme antagonistes et/ou suragonistes de la molécule de type sauvage dans le processus angiogénique. On peut préparer ces dérivés, ainsi que le bFGF de type sauvage, à l'aide de souches de $i(E. coli) ayant été transformées à l'aide de plasmides portant une séquence de nucléotides codant pour le bFGF humain et bovin ainsi que leurs dérivés.
Designated States: AU, DK, FI, HU, JP, KR, NO, SU, US.
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE).
Publication Language: English (EN)
Filing Language: English (EN)