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Machine translation
1. (WO1990002569) PRODUCTION OF CHIMERIC MOUSE-HUMAN ANTIBODIES WITH SPECIFICITY TO HUMAN TUMOR ANTIGENS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1990/002569    International Application No.:    PCT/US1989/003852
Publication Date: 22.03.1990 International Filing Date: 06.09.1989
Chapter 2 Demand Filed:    05.04.1990    
IPC:
A61K 38/00 (2006.01), C07K 16/46 (2006.01), G01N 33/531 (2006.01), G01N 33/574 (2006.01)
Applicants: INTERNATIONAL GENETIC ENGINEERING, INC. [US/US]; 1545-17th Street, Santa Monica, CA 90404 (US) (For All Designated States Except US).
BETTER, Marc, D. [US/US]; (US) (For US Only).
HORWITZ, Arnold, H. [US/US]; (US) (For US Only).
ROBINSON, Randy, R. [US/US]; (US) (For US Only).
LEI, Shau-Ping [CN/US]; (US) (For US Only).
CHANG, Changtung, Paul [CN/US]; (US) (For US Only)
Inventors: BETTER, Marc, D.; (US).
HORWITZ, Arnold, H.; (US).
ROBINSON, Randy, R.; (US).
LEI, Shau-Ping; (US).
CHANG, Changtung, Paul; (US)
Agent: GOLDSTEIN, Jorge, A.; Saidman, Sterne, Kessler & Goldstein, 1225 Connecticut Avenue, N.W., Suite 300, Washington, DC 20036 (US)
Priority Data:
240,624 06.09.1988 US
241,744 08.09.1988 US
243,739 13.09.1988 US
253,002 04.10.1988 US
367,641 19.06.1989 US
382,768 21.07.1989 US
Title (EN) PRODUCTION OF CHIMERIC MOUSE-HUMAN ANTIBODIES WITH SPECIFICITY TO HUMAN TUMOR ANTIGENS
(FR) PRODUCTION D'ANTICORPS CHIMERIQUES MURINS-HUMAINS A SPECIFICITE POUR DES ANTIGENES DE TUMEURS HUMAINS
Abstract: front page image
(EN)Gene expression elements and their use in production of chimeric antibodies with human constant regions and murine variable regions, and mouse human chimeric antibodies having specificity to human tumor cells, methods of their production, and their use.
(FR)L'invention concerne des éléments d'expression de gènes ainsi que leur utilisation dans la production d'anticorps chimériques à l'aide de régions humaines constantes et de régions murines variables, ainsi que des anticorps chimériques murins-humains, des procédés permettant leur production, et leur utilisation.
Designated States: AU, BR, DK, FI, JP, KR, NO, US.
Publication Language: English (EN)
Filing Language: English (EN)