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1. (WO1989009830) SUBTILISIN MUTATIONS

Pub. No.:    WO/1989/009830    International Application No.:    PCT/US1989/001475
Publication Date: Oct 19, 1989 International Filing Date: Apr 10, 1989
IPC: C12N 9/54
Applicants: GENEX CORPORATION
Inventors: BRYAN, Philip N.
PANTOLIANO, Michael W.
Title: SUBTILISIN MUTATIONS
Abstract:
The invention relates to subtilisin enzymes which have been modified by mutating a nucleotide sequence (gene) coding for the subtilisin. The modified subtilisin enzymes have enhanced thermal stability.