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1. WO1989009600 - METHOD AND COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS

Publication Number WO/1989/009600
Publication Date 19.10.1989
International Application No. PCT/US1989/001402
International Filing Date 04.04.1989
Chapter 2 Demand Filed 04.12.1989
IPC
A61K 31/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
14Quaternary ammonium compounds, e.g. edrophonium, choline
A61K 45/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
CPC
A61K 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
14Quaternary ammonium compounds, e.g. edrophonium, choline
A61K 31/685
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
685one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 25/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
02for peripheral neuropathies
A61P 25/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
A61P 25/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants
  • MASSACHUSETTS INSTITUTE OF TECHNOLOGY [US]/[US]
Inventors
  • WURTMAN, Richard, J.
  • BUYUKUYSAL, Rifat, Levent
Agents
  • GRANAHAN, Patricia @
Priority Data
179,59008.04.1988US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD AND COMPOSITION FOR TREATING NEUROLOGICAL DISORDERS
(FR) PROCEDE ET COMPOSITION DE TRAITEMENT DE TROUBLES NEUROLOGIQUES
Abstract
(EN)
Compositions useful in the treatment of neurological degenerative disorders which affect cholinergic neurons, as well as methods of use therefor. The compositions include a combination of a neural voltage-dependent potassium blocker and choline or a source of choline.
(FR)
On a mis au point des compositions utiles dans le traitement de troubles dégénératifs neurologiques affectant les neurones cholinergiques, ainsi que des procédés d'utilisations prévus à cet effet. Lesdites compositions comprennent un bloqueur de potassium dépendant de la tension neuronale ainsi que de la choline ou une source de choline combinés.
Also published as
Latest bibliographic data on file with the International Bureau