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1. (WO1989009598) PLATINUM-AMINE-SULFOXIDES AS ANTI-TUMOR AGENTS

Pub. No.:    WO/1989/009598    International Application No.:    PCT/US1989/001520
Publication Date: Oct 19, 1989 International Filing Date: Apr 12, 1989
IPC: C07F 15/00
Applicants: FARRELL, Nicholas, P.
THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL C
Inventors: FARRELL, Nicholas, P.
Title: PLATINUM-AMINE-SULFOXIDES AS ANTI-TUMOR AGENTS
Abstract:
Platinum complexes of the formulae [Pt(am)2ClR'R"SO]+X- and [Pt(am)¿2?SO4R'R"SO], wherein (am)2 represents a bidentate amine, R' and R" are different organic groups and X?-¿ is an anion, exhibit favorable anti-tumor acitivity in vivo against tumors susceptible to therapy with platinum.