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1. (WO1989009598) PLATINUM-AMINE-SULFOXIDES AS ANTI-TUMOR AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1989/009598 International Application No.: PCT/US1989/001520
Publication Date: 19.10.1989 International Filing Date: 12.04.1989
Chapter 2 Demand Filed: 05.12.1989
IPC:
C07F 15/00 (2006.01)
Applicants: FARRELL, Nicholas, P.[IE/US]; US (UsOnly)
THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL C[US/US]; OLLEGE; Burlington, VT 05405, US (AllExceptUS)
Inventors: FARRELL, Nicholas, P.; US
Agent: MURRAY, Robert, B.; Armstrong, Nikaido, Marmelstein, Kubovcik & Murray Suite 1000 1725 K Street, N.W. Washington, DC 20006, US
Priority Data:
180,95613.04.1988US
Title (EN) PLATINUM-AMINE-SULFOXIDES AS ANTI-TUMOR AGENTS
(FR) SULFOXYDES D'AMINE DE PLATINE EN TANT QU'AGENTS ANTI-TUMORAUX
Abstract:
(EN) Platinum complexes of the formulae [Pt(am)2ClR'R"SO]+X- and [Pt(am)2SO4R'R"SO], wherein (am)2 represents a bidentate amine, R' and R" are different organic groups and X- is an anion, exhibit favorable anti-tumor acitivity in vivo against tumors susceptible to therapy with platinum.
(FR) Des complexes au platine ayant les formules [Pt(am)2ClR'R"SO]+X- et [Pt(am)2SO4R'R"SO], dans lesquelles (am)2 représente une amine bidentée, R' et R" sont des groupes organiques différents et X- représente un anion, présentent une acitivité anti-tumorale favorable in vivo contre des tumeurs susceptibles d'être traitées au platine.
Designated States: AT, AU, BB, BG, BR, CH, DE, DK, FI, GB, HU, JP, KP, KR, LK, LU, MC, MG, MW, NL, NO, RO, SD, SE, SU, US
European Patent Office (EPO) (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)