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1. (WO1989009069) MEDICAL MATERIAL AND PROCESS FOR THEIR PRODUCTION

Pub. No.:    WO/1989/009069    International Application No.:    PCT/JP1989/000275
Publication Date: Oct 5, 1989 International Filing Date: Mar 15, 1989
IPC: A61L 33/00
C08L 63/00
C08L 63/06
Applicants: TERUMO KABUSHIKI KAISHA

SASAKI, Masatomi

KANEDA, Shinichi

KASHIWAGI, Nobuyoshi

Inventors: SASAKI, Masatomi

KANEDA, Shinichi

KASHIWAGI, Nobuyoshi

Title: MEDICAL MATERIAL AND PROCESS FOR THEIR PRODUCTION
Abstract:
A medical material, an intermediate (polymeric material) therefor and a process for their production are disclosed. The medical material comprises a polymeric material having many epoxy groups bound to the functional groups of a polymer having functional groups capable of binding with an epoxy group and to the amino group of a compound having two or more amino groups whose amino group not binding with an epoxy group is bound to an epoxy group of a heparin derivative wherein the epoxy group of an epoxy compound having two or more epoxy groups is bound to the amino groups of heparin. This material carries heparin in a large amount without losing its activity and has excellent biocompatibility. The intermediate and the process help to increase the advantages of the above-described medical material.