Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1989007452) IMPROVEMENTS IN OR RELATING TO ANTIBODIES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1989/007452 International Application No.: PCT/GB1989/000113
Publication Date: 24.08.1989 International Filing Date: 10.02.1989
IPC:
C07K 16/28 (2006.01) ,C07K 16/46 (2006.01) ,A61K 38/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
28
against receptors, cell surface antigens or cell surface determinants
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46
Hybrid immunoglobulins
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
Applicants:
MEDICAL RESEARCH COUNCIL [GB/GB]; 20 Park Crescent London W1N 4AL, GB (AllExceptUS)
WALDMANN, Herman [GB/GB]; GB
CLARK, Michael, Ronald [GB/GB]; GB
WINTER, Gregory, Paul [GB/GB]; GB (UsOnly)
RIECHMANN, Lutz [DE/US]; US (UsOnly)
Inventors:
WALDMANN, Herman; GB
CLARK, Michael, Ronald; GB
WINTER, Gregory, Paul; GB
RIECHMANN, Lutz; US
Agent:
KEITH W NASH & CO; Pearl Assurance House 90-92 Regent Street Cambridge CB2 1DP, GB
Priority Data:
880322812.02.1988GB
880446425.02.1988GB
Title (EN) IMPROVEMENTS IN OR RELATING TO ANTIBODIES
(FR) AMELIORATIONS RELATIVES A DES ANTICORPS
Abstract:
(EN) An antibody is produced, which will bind effectively with the antigen Campath-1, and which has at least one complementarity determining region of rat origin, as identified in Figure 2, which may be combined with a range of different foreign variable domain framework regions as desired, including framework regions of human origin.
(FR) On a produit un anticorps se liant effectivement à l'antigène Campath-1, et comportant au moins une région déterminante complémentaire d'origine de murine, telle qu'elle est identifiée dans la figure 2. On peut le combiner avec une gamme de régions étrangères différentes à structure de domaine variable selon ce que l'on veut, y compris des régions structurelles d'origine humaine.
Designated States: AU, DK, JP, US
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
JP3121823JPH02503514DKPR 174854AU1989030626