WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO1989003683) 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1989/003683    International Application No.:    PCT/US1988/003634
Publication Date: 05.05.1989 International Filing Date: 18.10.1988
Chapter 2 Demand Filed:    22.06.1989    
IPC:
C07H 21/00 (2006.01)
Applicants: TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HI [US/US]; GHER EDUCATION;, Philadelphia, PA 19122 (US)
Inventors: SUHADOLNIK, Robert, J.; (US).
PFLEIDERER, Wolfgang; (DE)
Agent: MONACO, Daniel, A.; Seidel, Gonda, Lavorgna & Monaco, 1800 Two Penn Center Plaza, Philadelphia, PA 19102 (US)
Priority Data:
112,591 22.10.1987 US
Title (EN) 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF
(FR) 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES ET LEURS UTILISATIONS ANTIVIRALES
Abstract: front page image
(EN)Optically active compounds of formula (I), wherein n is 1 or 2 and m is 0, 1, 2 or 3, have antiviral activity. Compounds of the formula wherein at least one of the internucleotide phosphorothioate linkages is of the Sp configuration possess increased antiviral activity and/or metabolic stability.
(FR)Composés optiquement actifs de formule (I) dans laquelle n est égal à 1 ou 2, et m est égal à 0, 1, 2 ou 3, ces composés ayant une activité antivirale. Dans les composés de la formule, au moins l'une des liaisons internucléotides phosphorothiotate a la configuration Sp. Les composés ont une activité antivirale et/ou une stabilité métabolique améliorée.
Designated States: AU, BB, BG, BR, DK, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, RO, SD, SU.
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
African Intellectual Property Organization (BJ, CF, CG, CM, GA, ML, MR, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)