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1. (WO1989000583) IMPROVED IMMUNOTOXIN THERAPIES UTILIZING PURIFIED RICIN A-CHAIN SPECIES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1989/000583 International Application No.: PCT/US1988/002343
Publication Date: 26.01.1989 International Filing Date: 12.07.1988
Chapter 2 Demand Filed: 13.03.1989
IPC:
A61K 47/48 (2006.01) ,A61K 51/10 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51
Preparations containing radioactive substances for use in therapy or testing in vivo
02
characterised by the carrier
04
Organic compounds
08
Peptides, e.g. proteins
10
Antibodies or immunoglobulins; Fragments thereof
Applicants:
XOMA CORPORATION [US/US]; 2910 Seventh Street Berkeley, CA 94710, US
Inventors:
SCANNON, Patrick, J.; US
KAWAHATA, Russell, T.; US
Agent:
SMITH, William, M.; Townsend and Townsend One Market Plaza 2000 Steuart Tower San Francisco, CA 94105, US
Priority Data:
074,82417.07.1987US
Title (EN) IMPROVED IMMUNOTOXIN THERAPIES UTILIZING PURIFIED RICIN A-CHAIN SPECIES
(FR) THERAPIES AMELIOREES A BASE D'IMMUNOTOXINES UTILISANT DES ESPECES A CHAINE-A DE RICINE PURIFIEE
Abstract:
(EN) Improved immunotoxin therapies are obtained by utilizing immunotoxins comprising ricin enriched in purified ricin A-chain species in conjunction with specific binding components, particularly monoclonal antibodies specifically reactive with markers of predetermined cell populations.
(FR) On obtient des thérapies améliorées à base d'immunotoxines en utilisant des immunotoxines comprenant de la ricine enrichie dans des espèces à chaîne-A de ricine purifiée, conjointement avec des éléments de liaison spécifique, tels que notamment des anticorps monoclonaux réagissant spécifiquement avec des marqueurs de populations de cellules prédéterminées.
Designated States: AU, JP, KR
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0419462AU1988021227