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1. (WO1989000446) AFFINITY SEPARATING USING IMMOBILIZED FLOCCULATING REAGENTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1989/000446 International Application No.: PCT/US1988/001779
Publication Date: 26.01.1989 International Filing Date: 02.06.1988
IPC:
B01D 15/08 (2006.01) ,G01N 33/539 (2006.01) ,G01N 33/553 (2006.01) ,G01N 30/52 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
D
SEPARATION
15
Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
08
Selective adsorption, e.g. chromatography
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
536
with immune complex formed in liquid phase
537
with separation of immune complex from unbound antigen or antibody
539
involving precipitating reagent
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
551
the carrier being inorganic
553
Metal or metal coated
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
30
Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography
02
Column chromatography
50
Conditioning of the sorbent material or stationary liquid
52
Physical parameters
Applicants:
E.I. DU PONT DE NEMOURS AND COMPANY [US/US]; 1007 Market Street Wilmington, DE 19898, US
Inventors:
LAU, Hon-Peng, Phillip; US
Agent:
FATO, Gildo, E.;; Du Pont Critical Care, Subsidiary of E.I. du Pont de Nemours & Co., (Inc.); 1600 Waukegan Road; Waukegan, IL 60085, US
Priority Data:
074,24216.07.1987US
Title (EN) AFFINITY SEPARATING USING IMMOBILIZED FLOCCULATING REAGENTS
(FR) PROCEDE DE SEPARATION PAR AFFINITE UTILISANT DES REACTIFS DE FLOCCULATION IMMOBILISES
Abstract:
(EN) Disclosed are solid supports including an immobilized flocculating agent which can be used as separation and assay media in the field of affinity separations and more particularly, in the field of clinical assays. In a specific embodiment, a flocculating agent such as polyethyleneimine is immobilized within a chromatographic support. The column so formed can then be used as an affinity column for affinity separations or immunoassays.
(FR) La présente invention décrit des supports solides comprenant un agent de flocculation immobilisé qui peut être utilisé comme moyen de séparation et d'analyse dans le domaine de séparation par affinité et plus particulièrement dans le domaine des analyses cliniques. Dans un mode de réalisation spécifique, un agent de flocculation tel que du polyéthylèneimine est immobilisé à l'intérieur d'un support chromatographique. La colonne ainsi formée peut ainsi être utilisée come colonne d'affinité pour effectuer des séparation ou des immuno-analyses par affinité.
Designated States: JP
European Patent Office (DE, FR, GB, IT, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0367795