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1. (WO1989000421) A PHARMACEUTICAL COMPOSITION CONTAINING S(+) IBUPROFEN SUBSTANTIALLY FREE OF ITS R(-) ANTIPODE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1989/000421 International Application No.: PCT/US1988/002253
Publication Date: 26.01.1989 International Filing Date: 08.07.1988
IPC:
A61K 31/19 (2006.01) ,C07C 57/30 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
57
Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
30
containing six-membered aromatic rings
Applicants:
SUNSHINE, Abraham [US/US]; US
LASKA, Eugene, M. [US/US]; US
Inventors:
SUNSHINE, Abraham; US
LASKA, Eugene, M.; US
Agent:
STEPNO, Norman, H. @; Burns, Doane, Swecker & Mathis The George Mason Building Washington & Prince Streets P.O. Box 1404 Alexandria, VA 22313-1404, US
Priority Data:
071,91410.07.1987US
Title (EN) A PHARMACEUTICAL COMPOSITION CONTAINING S(+) IBUPROFEN SUBSTANTIALLY FREE OF ITS R(-) ANTIPODE
(FR) COMPOSITION PHARMACEUTIQUE CONTENANT DE L'IBUPROFEN S(+) SENSIBLEMENT EXEMPT DE SON ANTIPODE R(-)
Abstract:
(EN) Onset-hastened and enhanced analgesic response is elicited in a mammalian organism in need of such treatment, i.e., a mammal suffering pain, by administering thereto a unit dosage onset-hastening/enhancing analgesically effective amount of the S(+) ibuprofen enantiomer, said enantiomer being substantially free of its R(-) ibuprofen antipode.
(FR) Une réponse analgésique accélérée dès la prise et augmentée est obtenue dans l'organisme d'un mammifère nécessitant un tel traitement, par exemple un mammifère souffrant de douleurs, en lui administrant une quantité unitaire d'une dose d'accélération dès la prise/augmentation de l'effet analgésique d'un énantiomère d'ibuprofen S(+), cet énantiomère étant sensiblement exempt de son antipode R(-) de l'ibuprofen.
Designated States: AU, JP
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0324007AU1988020803AU1999015494