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1. (WO1989000196) VIRUS PROTEINS HAVING REDUCED O-LINKED GLYCOSYLATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1989/000196 International Application No.: PCT/US1988/002021
Publication Date: 12.01.1989 International Filing Date: 17.06.1988
Chapter 2 Demand Filed: 26.01.1989
IPC:
C07K 14/03 (2006.01) ,C12N 15/866 (2006.01) ,A61K 39/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
01
DNA viruses
03
Herpetoviridae, e.g. pseudorabies virus
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
86
Viral vectors
866
Baculoviral vectors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants:
THE UPJOHN COMPANY [US/US]; 301 Henrietta Street Kalamazoo, MI 49001, US (AllExceptUS)
THOMSEN, Darrell R. [US/US]; US (UsOnly)
POST, Leonard, E. [US/US]; US (UsOnly)
Inventors:
THOMSEN, Darrell R.; US
POST, Leonard, E.; US
Agent:
KOIVUNIEMI, Paul, J.; Patent Law Department The Upjohn Company Kalamazoo, MI 49001, US
PERRY, Robert, E.; Gill Jennings & Every 53-64 Chancery Lane London WC2A 1HN, GB
Priority Data:
068,21130.06.1987US
Title (EN) VIRUS PROTEINS HAVING REDUCED O-LINKED GLYCOSYLATION
(FR) PROTEINES VIRALES PRESENTANT UNE GLYCOSYLATION A LIAISON O REDUITE
Abstract:
(EN) The present invention provides viral glycoproteins having a lower amount of O-linked glycosylation than the naturally occurring glycoprotein. These glycoproteins are produced in insect host cells infected with a recombinant DNA molecule comprising a baculovirus vector and the DNA sequence encoding said glycoprotein. The present invention also provides subunit vaccines for pseudorabies virus.
(FR) La présente invention se rapporte à des protéines virales présentant une teneur en glycosylation à liaison O inférieure par rapport à la glycoprotéine présente naturellement. Ces glycoprotéines sont produites dans des cellules hôtes d'insectes infectées avec une molécule d'ADN recombinant comprenant un vecteur de baculovirus et la séquence d'ADN codant pour ladite glycoprotéine. La présente invention se rapporte également à des vaccins sous-unitaires pour virus pseudorabiques.
Designated States: AU, DK, FI, JP, KR, NO
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0364492KR1019890701745AU1988020837