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1. (WO1989000168) NOVEL INTERLEUKIN-2 RECEPTOR AND APPLICATIONS THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1989/000168 International Application No.: PCT/US1988/001806
Publication Date: 12.01.1989 International Filing Date: 27.05.1988
IPC:
A61K 47/48 (2006.01) ,C07K 14/55 (2006.01) ,C07K 14/715 (2006.01) ,A61K 38/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
48
the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
52
Cytokines; Lymphokines; Interferons
54
Interleukins (IL)
55
IL-2
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
715
for cytokines; for lymphokines; for interferons
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
Applicants:
THE UNITED STATES OF AMERICA, as represented by TH [US/US]; E SECRETARY, U.S. DEPARTMENT OF COMMERCE; 5285 Port Royal Road; Springfield, VA 22151, US
Inventors:
WALDMANN, Thomas, A.; US
LEONARD, Warren, J.; US
Agent:
STERN, Marvin, R. @; Holman & Stern 2401 Fifteenth Street, N.W. Washington, DC 20009, US
Priority Data:
066,98929.06.1987US
165,30203.03.1988US
Title (EN) NOVEL INTERLEUKIN-2 RECEPTOR AND APPLICATIONS THEREOF
(FR) NOUVEAU RECEPTEUR D'INTERLEUKINE 2 ET SES APPLICATIONS
Abstract:
(EN) The present invention is related to the field of receptor molecules and complexes. More particularly, the present invention is related to a new polypeptide receptor for interleukin-2 having a molecular weight of about 70-75,000, which is a component of the high affinity IL-2 receptor, antibodies against this new polypeptide, and recombinant interleukins capable of binding to the new receptor. Various applications of the p70-75 receptor, the anti-p70-75 antibodies and IL-2W1 and IL-2W2 have also been described.
(FR) La présente invention se rapporte au domaine des molécules et complexes récepteurs, et plus précisément à un nouveau récepteur de polypeptides destinés à l'interleukine 2, dont le poids moléculaire est d'environ 70 à 75000, et qui est un constituant du récepteur de l'IL-2 à haute affinité, à des anticorps dressés contre ce nouveau polypeptide, ainsi qu'à des interleukines recombinantes capables de lier le nouveau récepteur. Sont également décrites diverses applications du récepteur p70-75, des anticorps anti p70-75 de l'IL-2W1 et de l'IL-2W2.
Designated States: AU, JP
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
AU1988019923