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1. (WO1989000157) ESTERS OF 13-TRANS-RETINOIC ACID
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1989/000157 International Application No.: PCT/US1988/002141
Publication Date: 12.01.1989 International Filing Date: 27.06.1988
Chapter 2 Demand Filed: 20.02.1989
IPC:
A61K 8/67 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
67
Vitamins
Applicants:
MOLECULAR DESIGN INTERNATIONAL, INC. [US/US]; P.O. Box 41777 Memphis, TN 38174, US
Inventors:
PARISH, Harlie, A.; US
PURCELL, William, P.; US
Agent:
WALDRON, James, S. @; Waldron & Associates 2120 L Street, N.W. Suite 200 Washington, DC 20037, US
Priority Data:
067,53629.06.1987US
Title (EN) ESTERS OF 13-TRANS-RETINOIC ACID
(FR) ESTERS D'ACIDE 13-TRANS RETINOIQUE
Abstract:
(EN) Esters and amides of 13-trans-retinoic acid are disclosed which are used for the treatment of acne and skin diseases. The derivatives have the formula (I) wherein R is (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l), (m), or (n) wherein X is -H, -F, -Cl, -Br, -I, -OH, -OR, -OR', (o), (p), (q), -CN, -NO2, -NH2, -NHR', or -NR'2; wherein n is a number from 1 to 5; wherein R' is H or any of the lower alkyls ranging from C1 to C6.
(FR) Sont décrits des esters et amides d'acide 13-trans rétinoïque utilisés dans le traitement de l'acné et de maladies de la peau. Les dérivés ont la formule (I) dans laquelle R représente (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), (k), (l), (m), ou (n), X représente -H, -F, -Cl, -Br, -I, -OH, -OR, -OR', (o), (p), (q), -CN, -NO2, -NH2, -NHR', ou NR'2; n représente un chiffre allant de 1 à 5; R' représente H ou n'importe lequel des alkyles se trouvant dans la plage allant de C1 à C6.
Designated States: AU, DK, JP
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0366713AU1988020809