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1. (WO1989000005) IMPROVED ASSAYS FOR t-PLASMINOGEN ACTIVATOR AND PLASMINOGEN ACTIVATOR INHIBITOR
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1989/000005 International Application No.: PCT/US1988/002277
Publication Date: 12.01.1989 International Filing Date: 05.07.1988
IPC:
C12Q 1/56 (2006.01) ,G01N 33/86 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
56
involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
86
involving blood coagulating time
Applicants:
CYTRX BIOPOOL LTD. [US/US]; 150 Technology Parkway Technology Park/Atlanta Norcross, GA 30092, US
Inventors:
RANBY, Mats, Gustaf; SE
WIMAN, Tor-Bjorn; SE
Agent:
GRAHAM, Jamie, L. @; CytRx Biopool Ltd. 150 Technology Parkway Technology Park/Atlanta Norcross, GA 30092, US
Priority Data:
070,06806.07.1987US
Title (EN) IMPROVED ASSAYS FOR t-PLASMINOGEN ACTIVATOR AND PLASMINOGEN ACTIVATOR INHIBITOR
(FR) ANALYSES AMELIOREES D'ACTIVATEUR PLASMINOGENE ET D'INHIBITEUR D'ACTIVATEUR PLASMINOGENE
Abstract:
(EN) The present invention relates to an improved method for measuring tissue plasminogen activator and plasminogen activator inhibitor. The method utilizes a genetically modified tissue plasminogen activator protein as a substrate. The present invention also relates to improved methods of collecting blood so that endogenous plasminogen activator is not inactivated.
(FR) Procédé amélioré permettant de mesurer un activateur plasminogène et un inhibiteur d'activateur plasminogène de tissus. Le procédé utilise comme substrat une protéine activatrice plasminogène de tissus. La présente invention se rapporte également à des procédés améliorés de prélèvement de sang permettant de ne pas activer l'activateur plasminogène endogène.
Designated States: AU, BB, BG, BR, DK, FI, HU, JP, KP, KR, LK, MC, MG, MW, NO, RO, SD, SU
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0324027EP0576038EP0576039DE000003856367AU1988023146