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1. (WO1987003691) DETERMINATION OF TEST SUBSTANCES
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1987/003691 International Application No.: PCT/US1986/002681
Publication Date: 18.06.1987 International Filing Date: 12.12.1986
IPC:
G01N 33/53 (2006.01) ,G01N 33/543 (2006.01) ,G01N 33/58 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58
involving labelled substances
Applicants:
DENNISON MANUFACTURING COMPANY [US/US]; 300 Howard Street Framingham, MA 01701, US
Inventors:
COLE, Francis; US
Agent:
KERSEY, George, E.; Dennison Manufacturing Company Patent Department 300 Howard Street Framingham, MA 01701, US
Priority Data:
807,93612.12.1985US
Title (EN) DETERMINATION OF TEST SUBSTANCES
(FR) DETERMINATION DE SUBSTANCES DE TEST
Abstract:
(EN) Determination of whether or not a test substance, such as a pregnancy antigen (AG), is present by combining (1) the test substance (AG) with a first labeled material, e.g. a first enzyme labeled antibody (ABA-E1) in a vial (30). The resulting product is added (2) to a second labeled material, e.g. a second enzyme labeled antibody (ABA-E2), bound to a membrane (22) which overlays a porous member (21) both within a housing (10) to which a substrate is applied (3) from vial (40) to react with one of the labels and produce a reagent that in turn reacts with an indicator and the other label to provide a test indication such as a color change.
(FR) Détermination de la présente ou de l'absence d'une substance de test, telle qu'un antigène de grossesse (AG), par combinaison (1) de la substance de test (AG) avec une première substance marquée, par exemple un premier anticorps marqué par une enzyme (ABA-E1) dans une éprouvette (30). Le produit résultant est ajouté (2) à une deuxième substance marquée, par exemple un deuxième anticoorps marqué par une enzyme (ABA-E1), fixé sur une membrane (22) recouvrant un organe poreux (21) à l'intérieur d'un logement (10), un substrat étant appliqué (3) à partir de l'éprouvette (40) pour qu'il réagisse avec l'un des marqueurs et produise un réactif réagissant à son tour avec un indicateur et avec l'autre marqueur pour fournir une indication du test, tel qu'un changement de couleur.
Designated States: JP
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0250557