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1. (WO1987003621) METHOD, KIT AND PRODUCT FOR DISEASE DIAGNOSIS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1987/003621 International Application No.: PCT/US1986/002594
Publication Date: 18.06.1987 International Filing Date: 02.12.1986
IPC:
C12Q 1/68 (2006.01) ,C12Q 1/70 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
70
involving virus or bacteriophage
Applicants:
EL-GEWELY, M., Raafat [EG/US]; US
Inventors:
EL-GEWELY, M., Raafat; US
Agent:
AUGSPURGER, Lynn, L.; 15999 West 12 Mile Road Southfield, MI 48076, US
Priority Data:
804,01403.12.1985US
Title (EN) METHOD, KIT AND PRODUCT FOR DISEASE DIAGNOSIS
(FR) PROCEDE, KIT ET PRODUIT POUR LE DIAGNOSTIC DE MALADIE
Abstract:
(EN) A method, product and kit for diagnosing disease utilizing nucleic acid hybridization. The nucleic acid probe is non-radioactive and comprises a reporter molecule bound to a nucleic acid sequence complementary to the nucleic acid sequence of the target disease organism. The probe is hybridized to the sequence of the target disease organism and the reporter molecule is detected after exposure to UV light. The method is used to detect the AIDS, HSV, CMV, HBV and HAV viruses as well as bacteria such as cholera, mycoplasma and chlamydia.
(FR) Procédé, produit et kit pour diagnostiquer des maladies en utilisant l'hybridation d'acides nucléiques. La sonde d'acides nucléiques est non-radioactive et comprend une molécule ''reporter'' liée à la séquence d'acides nucléiques complémentaire à la séquence d'acides nucléiques de l'organisme cible malade. La sonde est hybridisée sur la séquence de l'organisme cible malade et la molécule ''reporter'' est détectée après exposition à la lumière UV. Le procédé est utilisé pour détecter les virus du SIDA, HSV, CMV, HBV et HAV ainsi des bactéries telles que le choléra, les mycoplasmes et le chlamydia.
Designated States: JP
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP0249628