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1. (WO1987003601) PEPTIDES CAPABLE OF INHIBITING THE INTERACTIONS BETWEEN ANTIGENS AND LYMPHOCYTES T4, PRODUCTS DERIVED THEREFROM AND APPLICATION THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1987/003601 International Application No.: PCT/FR1986/000425
Publication Date: 18.06.1987 International Filing Date: 08.12.1986
IPC:
C07K 14/16 (2006.01) ,C07K 14/74 (2006.01) ,A61K 38/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
08
RNA viruses
15
Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
155
Lentiviridae, e.g. human immunodeficiency virus (HIV), visna-maedi virus, equine infectious anaemia virus
16
HIV-1
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
705
Receptors; Cell surface antigens; Cell surface determinants
74
Major histocompatibility complex (MHC)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
Applicants:
INSTITUT PASTEUR [FR/FR]; 25-28, rue du Dr. Roux F-75724 Paris Cédex 15, FR (AllExceptUS)
AUFFRAY, Charles [FR/FR]; FR (UsOnly)
MONTAGNIER, Luc [FR/FR]; FR (UsOnly)
KLATZMANN, David [FR/FR]; FR (UsOnly)
FISHER, Alain [FR/FR]; FR (UsOnly)
CHARRON, Dominique [FR/FR]; FR (UsOnly)
Inventors:
AUFFRAY, Charles; FR
MONTAGNIER, Luc; FR
KLATZMANN, David; FR
FISHER, Alain; FR
CHARRON, Dominique; FR
Agent:
PLASSERAUD, Yves @; S.C. Ernest Gutmann-Yves Plasseraud 67, boulevard Hausmann F-75008 Paris, FR
Priority Data:
85/1815506.12.1985FR
Title (EN) PEPTIDES CAPABLE OF INHIBITING THE INTERACTIONS BETWEEN ANTIGENS AND LYMPHOCYTES T4, PRODUCTS DERIVED THEREFROM AND APPLICATION THEREOF
(FR) PEPTIDES CAPABLES D'INHIBER LES INTERACTIONS ENTRE DES ANTIGENES ET LES LYMPHOCYTES T4, PRODUITS QUI EN SONT DERIVES ET LEURS APPLICATIONS
Abstract:
(EN) Polypeptide having the capacity of inhibiting the interaction of the virus held to be responsible for AIDS with the receivers T4 carried by the lymphocytes T4. Said peptide is selected amongst those which are represented amongst the general formulas: X-RFDS-Z, X-SDFR-Z, X-SDAR-Z, X-RADS-Z wherein X is a hydrogen atom or a peptidic group, Z is OH or a peptidic group, and the other letters represent specific amino acids (specification of amino acids designated by a single letter).
(FR) Un polypeptide ayant la capacité d'inhiber l'interaction du virus tenu pour responsable du SIDA avec les récepteurs T4 portés par les lymphocytes T4. Ce peptide est choisi parmi ceux qui sont représentés parmi les formules générales: X-RFDS-Z, X-SDFR-Z, X-SDAR-Z, X-RADS-Z, dans lesquelles X est un atome d'hydrogène ou un groupe peptidique, Z est OH ou un groupe peptidique, et les autres lettres désignent des aminoacides spécifiques (nomenclature de désignation à une lettre des aminoacides).
Designated States: DK, JP, US
Publication Language: French (FR)
Filing Language: French (FR)