Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO1987003485) COMPOSITIONS FOR COMBATTING DIARRHOEA
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1987/003485 International Application No.: PCT/NL1986/000041
Publication Date: 18.06.1987 International Filing Date: 09.12.1986
IPC:
C07K 14/245 (2006.01) ,C07K 5/083 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195
from bacteria
24
from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
245
Escherichia (G)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
5
Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04
containing only normal peptide links
08
Tripeptides
083
the side chain of the first amino acid being acyclic, e.g. Gly, Ala
Applicants:
VERENIGING VOOR CHRISTELIJK WETENSCHAPPELIJK ONDER [NL/NL]; WIJS; P.O. Box 7161 NL-1007 MC Amsterdam, NL (AllExceptUS)
DE GRAAF, Frits, Karel [NL/NL]; NL (UsOnly)
JACOBS, Antonius, Arnoldus, Christiaan [NL/NL]; NL (UsOnly)
Inventors:
DE GRAAF, Frits, Karel; NL
JACOBS, Antonius, Arnoldus, Christiaan; NL
Agent:
KOOY, Leendert, Willem; Octrooibureau Vriesendorp & Gaade P.O. Box 266 NL-2501 AW The Hague, NL
Priority Data:
850341311.12.1985NL
Title (EN) COMPOSITIONS FOR COMBATTING DIARRHOEA
(FR) COMPOSITION POUR LE TRAITEMENT DE LA DIARRHEE
Abstract:
(EN) A therapeutical composition for combatting and preventing diarrhoea. Said composition comprises one or more substances which block adhesine receptors present on the intestinal epithelium. Preferably said substances are peptides, in particular Ser-Leu-Phe, Ile-Ala-Phe and/or Ala-Ile-Phe.
(FR) Une composition thérapeutique pour le traitement et la prévention de la diarrhée comprend une ou plusieurs substances qui arrêtent les récepteurs d'adhésine présents sur l'épithélium intestinal. Lesdites substances sont de préférence des peptides, en particulier de Ser-Leu-Phe, de Ile-Ala-Phe et/ou de Ala-Ile-Phe.
Designated States: JP, US
European Patent Office (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: Dutch (NL)
Also published as:
EP0248838