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1. WO1986006744 - A cDNA MOLECULE CODING FOR THE EXPRESSION OF AN INTERFERON $g(a) TYPE POLYPEPTIDE, A BACTERIAL OR CELLULAR HOST TRANSFORMED WITH SUCH MOLECULE AND A POLYPEPTIDE SHOWING INTERFERON ACTIVITY PREPARED BY SUCH HOST

Publication Number WO/1986/006744
Publication Date 20.11.1986
International Application No. PCT/SE1986/000228
International Filing Date 14.05.1986
IPC
C07K 14/56 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
52Cytokines; Lymphokines; Interferons
555Interferons (IFN)
56IFN-alpha
CPC
C07K 14/56
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
52Cytokines; Lymphokines; Interferons
555Interferons [IFN]
56IFN-alpha
Applicants
  • KABIVITRUM AB [SE]/[SE] (AllExceptUS)
  • VON GABAIN, Alexander, Ulrich [DE]/[SE] (UsOnly)
  • LUND, Björn, Olof [SE]/[SE] (UsOnly)
  • EDLUND, Thomas, Bernhard [SE]/[SE] (UsOnly)
  • NY, Tor, Erik, Roger [SE]/[SE] (UsOnly)
  • LUNDGREN, Erik, Hugo, Olaus [SE]/[SE] (UsOnly)
Inventors
  • VON GABAIN, Alexander, Ulrich
  • LUND, Björn, Olof
  • EDLUND, Thomas, Bernhard
  • NY, Tor, Erik, Roger
  • LUNDGREN, Erik, Hugo, Olaus
Agents
  • BURMAN, Tore @
Priority Data
8502430-515.05.1985SE
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) A cDNA MOLECULE CODING FOR THE EXPRESSION OF AN INTERFERON $g(a) TYPE POLYPEPTIDE, A BACTERIAL OR CELLULAR HOST TRANSFORMED WITH SUCH MOLECULE AND A POLYPEPTIDE SHOWING INTERFERON ACTIVITY PREPARED BY SUCH HOST
(FR) MOLECULE D'ADNc CODANT POUR L'EXPRESSION D'UN POLYPEPTIDE $i(a) D'INTERFERON, HOTE BACTERIEN OU CELLULAIRE TRANSFORME A L'AIDE DE CETTE MOLECULE ET POLYPEPTIDE PREPARE PAR LEDIT HOTE ET PRESENTANT UNE ACTIVITE D'INTERFERON
Abstract
(EN) A cDNA molecule having the nucleotide sequence ($g(a)-88) (I) or sequences which hybridize to the foregoing sequence and which code for the expression of a polypeptide of the IFN-$g(a) type; or sequences which are degenerate as a result of the genetic code to the nucleotide sequence defined above and which code for the expression of a polypeptide of the IFN-$g(a) type; a bacterial or cellular host transformed with such molecule; a polypeptide having $g(a)-type interfering activity prepared by such host; and method of therapeutical treatment.
(FR) Molécule d'ADNc possédant la séquence de nucléotide ($g(a)-88) (I) ou séquences subissant une hybridation en la séquence précédente et qui codent l'expression d'un polypeptide du type IFN-$g(a), ou séquences qui dégénèrent à la suite du code génétique en la séquence de nucléotide définie ci-dessus et qui codent l'expression d'un polypeptide du type IFN-$g(a); un hôte bactérien ou cellulaire transformé par cette molécule; un polypeptide possédant une activité d'interféron du type $g(a) préparé par ledit hôte, et procédé de traitement thérapeutique.
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