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1. WO1986006626 - METHOD OF PREPARING AN EXTEMPORANEOUS HOMOGENEOUS MICROCAPSULE SUSPENSION

Publication Number WO/1986/006626
Publication Date 20.11.1986
International Application No. PCT/EP1986/000280
International Filing Date 02.05.1986
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 9/50 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules
CPC
A61K 9/0095
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0087Galenical forms not covered by A61K9/02 - A61K9/7023
0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
A61K 9/5047
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
5005Wall or coating material
5021Organic macromolecular compounds
5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
A61K 9/5057
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
5005Wall or coating material
5021Organic macromolecular compounds
5052Proteins, e.g. albumin
5057Gelatin
Y10S 514/952
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
951Powders, granules or particles of specified mesh or particle size
952Wettable
Y10S 514/974
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
974Containing designated ingredient to reduce noxious effects of active ingredient, e.g. taste masking, odor reducing
Y10T 428/2989
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
428Stock material or miscellaneous articles
29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
2982Particulate matter [e.g., sphere, flake, etc.]
2989Microcapsule with solid core [includes liposome]
Applicants
  • EURAND ITALIA S.p.A. [IT]/[IT] (AllExceptUS)
  • CALANCHI, Massimo [IT]/[IT] (UsOnly)
  • GENTILINI, Leonardo [IT]/[IT] (UsOnly)
  • MARCONI, Marco [IT]/[IT] (UsOnly)
Inventors
  • CALANCHI, Massimo
  • GENTILINI, Leonardo
  • MARCONI, Marco
Agents
  • RICCARDI, Sergio
Priority Data
20617 A/8508.05.1985IT
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD OF PREPARING AN EXTEMPORANEOUS HOMOGENEOUS MICROCAPSULE SUSPENSION
(FR) PROCEDE DE PREPARATION D'UNE SUSPENSION EXTEMPORANEE HOMOGENE EN MICROCAPSULES
Abstract
(EN)
Method by which it is possible to prepare a formulation consisting of thickening or suspending agents and other excipients, having the property of dispersing and dissolving quickly in water or aqueous vehicles, without clot formation, with which it is possible to prepare an extemporaneous homogeneous suspension of solid particles and more particularly of microencapsulated drugs, which otherwise would have the tendency to precipitate or float, the method being however useful in all those cases where it is necessary to keep in suspension particles of substances showing the above mentioned tendency.
(FR)
Procédé permettant de préparer une formulation composée d'agents épaississants ou de suspension et d'autres excipients, ayant la propriété de se disperser et de se dissoudre rapidement dans l'eau ou des véhicules aqueux, sans formation de grumeaux, avec lesquels il est possible de préparer une suspension extemporanée homogène de particules solides et plus particulièrement de médicaments microencapsulés, qui autrement auraient tendance à précipiter ou à flotter. Ce procédé est utile dans tous les cas où il est nécessaire de maintenir en suspension des particules de substances présentant la tendance précitée.
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