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1. (WO1986000930) RETROVIRAL VACCINES AND VECTORS AND METHODS FOR THEIR CONSTRUCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/1986/000930 International Application No.: PCT/US1985/001352
Publication Date: 13.02.1986 International Filing Date: 18.07.1985
IPC:
C07K 14/15 (2006.01) ,C12N 15/867 (2006.01) ,A61K 38/00 (2006.01) ,A61K 39/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005
from viruses
08
RNA viruses
15
Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
86
Viral vectors
867
Retroviral vectors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
Applicants: WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY[US/US]; 222 Maple Avenue Shrewsbury, MA 01545, US
Inventors: ROBINSON, Harriet; US
Agent: BROOK, David, E. @; Hamilton, Brook, Smith and Reynolds Two Militia Drive Lexington, MA 02173, US
Priority Data:
632,72320.07.1984US
Title (EN) RETROVIRAL VACCINES AND VECTORS AND METHODS FOR THEIR CONSTRUCTION
(FR) VACCINS ET VECTEURS RETROVIRAUX, ET METHODES POUR LEUR CONSTRUCTION
Abstract:
(EN) Retroviruses and retrovirus vectors that either are or are not shed into eggs and therefore either do or do not undergo congenital transmission, and methods for making them. This invention is based on the discovery that the ability of exogenous avian leukosis viruses to undergo congenital transmission is determined by $i(gag) sequences of the viral genome.
(FR) Une description est donnée concernant des rétrovirus et des vecteurs de rétrovirus qui sont ou ne sont pas déposés dans des oeufs, et par conséquent sont ou ne sont pas soumis à une transmission congénitale, ainsi que des méthodes pour leur production. Cette invention est basée sur la découverte du fait que la capacité qu'ont les virus exogènes de la leucose chez les aviens à subir une transmission congénitale est déterminée par des séquences $i(gag) du génome viral.
Designated States: JP
European Patent Office (EPO) (AT, BE, CH, DE, FR, GB, IT, LU, NL, SE)
Publication Language: English (EN)
Filing Language: English (EN)