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1. (WO1985003933) PROCESS FOR PREPARING N-ACYLPHENYLALANINES

Pub. No.:    WO/1985/003933    International Application No.:    PCT/JP1985/000109
Publication Date: Sep 12, 1985 International Filing Date: Mar 5, 1985
IPC: C07C 233/12
C07C 233/45
Applicants: MITSUI TOATSU CHEMICALS, INCORPORATED

MITA, Ryuichi

KATOH, Toshio

HIGUCHI, Chojiro

YAMAGUCHI, Akihiro

Inventors: MITA, Ryuichi

KATOH, Toshio

HIGUCHI, Chojiro

YAMAGUCHI, Akihiro

Title: PROCESS FOR PREPARING N-ACYLPHENYLALANINES
Abstract:
A process for preparing N-acylphenylalanines represented by formula (II): wherein R?3 and R4¿ each represents a hydrogen atom, an alkyl group, an alkoxy group, a phenoxy group, a hydroxy group or a methylenedioxy group, R represents a methyl group or a phenyl group, by catalytic reduction of an N-acyl-β-phenylserine represented by formula (I): wherein R?1 and R2¿ each represents a hydrogen atom, an alkyl group, an alkoxy group, a phenoxy group, a benzyloxy group or a methylenedioxy group, and R is as defined above, in a solvent in the presence of a reducing catalyst or both a reducing catalyst and an acid.