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1. (WO1985003300) 1α,25-DIHYDROXY-22Z-DEHYDROVITAMIN D COMPOUND

Pub. No.:    WO/1985/003300    International Application No.:    PCT/US1985/000017
Publication Date: Aug 1, 1985 International Filing Date: Jan 7, 1985
IPC: C07C 401/00
C07J 71/00
C07J 9/00
Applicants: WISCONSIN ALUMNI RESEARCH FOUNDATION
Inventors: DeLUCA, Hector, F.
SCHNOES, Heinrich, K.
SICINSKI, Rafal, R.
TANAKA, Yoko
Title: 1α,25-DIHYDROXY-22Z-DEHYDROVITAMIN D COMPOUND
Abstract:
Novel vitamin D derivative, 1α,25-dihydroxy-22Z-dehydrovitamin D2. The compound is characterized by unexpectedly high ability to raise serum calcium levels. The compound could therefore, find ready application as a substitute for vitamin D or its metabolites in the treatment of metabolic bone diseases or in other of their known applications.