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1. WO1985002541 - CHROMONE-2-CARBOXILIC ACID DERIVATIVES AS CARDIOVASCULAR AGENTS

Publication Number WO/1985/002541
Publication Date 20.06.1985
International Application No. PCT/GB1984/000395
International Filing Date 19.11.1984
IPC
A61K 31/35 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
CPC
A61K 31/35
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
Applicants
  • FISONS PLC [GB]/[GB] (AllExceptUS)
  • SHEARD, Philip [GB]/[GB] (UsOnly)
Inventors
  • SHEARD, Philip
Agents
  • CRAIG, Christopher, Bradberry
Priority Data
833245006.12.1983GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CHROMONE-2-CARBOXILIC ACID DERIVATIVES AS CARDIOVASCULAR AGENTS
(FR) DERIVES DE L'ACIDE CHROMONE-2-CARBOXYLIQUE UTILISES COMME AGENTS CARDIO-VASCULAIRES
Abstract
(EN)
Method of treatment of a cardiovascular condition, e.g. the cardiovascular sequelae of hypoxia, which method comprises administration of an effective amount of a compound of formula (I), wherein X is a polymethylene chain containing 3 to 7 carbon atoms inclusive, which chain may be substituted by an -OH group, or a pharmaceutically acceptable salt, alkyl C 1 to 10 ester, mono-alkyl C 1 to 10 amide, di-alkyl C 1 to 10 amide or unsubsituted amide hereof, or of an anti-leukotrine compound as herein defined (as active ingredient), to a human patient suffering from the cardiovascular condition.
(FR)
Procédé de traitement de troubles cardio-vasculaires, par exemple des séquelles cardio-vasculaires de l'hypoxie, consistant à administrer à un patient humain souffrant de troubles cardio-vasculaires une quantité efficace d'un composé de formule (I), où X est une chaîne de polyméthylène contenant de 3 à 7 atomes de carbone, cette chaîne pouvant être substituée par un groupe -OH, ou alors X est un sel pharmaceutiquement acceptable, un ester d'alkyle comportant de 1 à 10 C, un amide de monoalkyle comportant de 1 à 10 C, un amide de di-alkyle comportant de 1 à 10 C ou son amide non substitué, ou d'un composé anti-leucotrine ainsi qu'il est défini ici (comme ingrédient actif).
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