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1. (WO1985002189) 1,25-DIHDROXYVITAMIN D2 COMPOUNDS AND METHODS FOR THEIR PREPARATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/1985/002189    International Application No.:    PCT/US1984/001334
Publication Date: 23.05.1985 International Filing Date: 20.08.1984
IPC:
C07C 401/00 (2006.01), C07J 71/00 (2006.01)
Applicants: WISCONSIN ALUMNI RESEARCH FOUNDATION [US/US]; 614 North Walnut Street, Madison, WI 53705 (US)
Inventors: DeLUCA, Hector, F.; (US).
SCHNOES, Heinrich, K.; (US).
SICINSKI, Rafal, R.; (PL).
TANAKA, Yoko; (US)
Agent: BREMER, Howard, W.; 614 North Walnut Street, Madison, WI 53705 (US)
Priority Data:
549,047 07.11.1983 US
Title (EN) 1,25-DIHDROXYVITAMIN D2 COMPOUNDS AND METHODS FOR THEIR PREPARATION
(FR) COMPOSES DE LA 1,25-DIHYDROXY-VITAMINE D2 ET LEURS PROCEDES DE PREPARATION
Abstract: front page image
(EN)Preparation of hydroxylated compounds of the vitamin D2 series and specifically to a process for synthesizing 1alpha,25-dihydroxy vitamin D2, 1beta,25-dihydroxyvitamin D2, their corresponding 5,6-trans isomers and the C-24 epimers of these compounds. The hydroxylated vitamin D2 compounds obtained exhibit vitamin D-like activity and can be substituted for vitamin D3 or various of its known metabolites where such compounds are applied.
(FR)Préparation de composés hydroxylés de la série de la vitamine D2 et procédé de synthèse de la 1alpha,25-dihydroxy-vitamine D2, 1beta,25-dihydroxy-vitamine D2, de leurs isomères correspondants 5,6-trans et des épimères à 24 C de ces composés. Les composés hydroxylés de vitamine D2 obtenus possèdent une activité similaire à celle de la vitamine D et peuvent remplacer la vitamine D3 ou plusieurs de ses métabolites connus lors de l'application de tels composés.
Designated States: AU, CH, DE, DK, JP, NL.
Publication Language: English (EN)
Filing Language: English (EN)