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1. (WO1984000106) ANESTHETIC-ANTIPRURITIC N-(3-(4-(3-FLUOROBENZYLOXY)PHENOXY)PROPYL)MORPHOLINE COMPOUNDS, COMPOSITIONS AND USE
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/1984/000106 International Application No.: PCT/US1983/000950
Publication Date: 19.01.1984 International Filing Date: 16.06.1983
IPC:
C07C 43/23 (2006.01) ,C07D 295/092 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
43
Ethers; Compounds having groups, groups or groups
02
Ethers
20
having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
23
containing hydroxy or O-metal groups
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
295
Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
04
with substituted hydrocarbon radicals attached to ring nitrogen atoms
08
substituted by singly bound oxygen or sulfur atoms
084
with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
092
with aromatic radicals attached to the chain
Applicants:
Inventors:
Priority Data:
null30.12.1899null
Title (EN) ANESTHETIC-ANTIPRURITIC N-(3-(4-(3-FLUOROBENZYLOXY)PHENOXY)PROPYL)MORPHOLINE COMPOUNDS, COMPOSITIONS AND USE
(FR) COMPOSES ANESTHESIQUES-ANTIPRURIGINEUX DE N-(3-(4-(3-FLUOROBENZYLOXY) PHENOXY) PROPYL) MORPHOLINE, COMPOSITIONS CONTENANT CES COMPOSES ET LEUR UTILISATION
Abstract:
(EN) N- AD3-(4- $(1,3)$3-Fluorobenzyloxy$(1,3)$ phenoxy)propyl BD-morpholine and its pharmaceutically acceptable salts possess topical anesthetic-antipruritic properties. The free base can be obtained by coupling an alkali metal salt of 4-(3-fluorobenzyloxy)phenol and N-(3-chloropropyl)-morpholine.
(FR) L'N- AD3-(4- 3-fluorobenzyloxy)phénoxy)propyl BD-morpholine et ses sels pharmaceutiquement acceptables possèdent des propriétés topiques anesthésiques-antiprurigineuses. La base libre peut être obtenue en couplant un sel métallique alcalin de 4-(3-fluorobenzyloxy)phénol et de N-(3-fluoropropyl)-morpholine.
Designated States:
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
NZ204638AU1983017779