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1. (WO1983000503) HUMAN NONSECRETORY PLASMACYTOID CELL LINE

Pub. No.:    WO/1983/000503    International Application No.:    PCT/US1982/001084
Publication Date: Fri Feb 18 00:59:59 CET 1983 International Filing Date: Wed Aug 11 01:59:59 CEST 1982
IPC: C07K 16/08
C12N 5/16
Applicants: RESEARCH CORPORATION
Inventors: RITTS, Roy, Ellot, Jr.
Title: HUMAN NONSECRETORY PLASMACYTOID CELL LINE
Abstract:
A human nonsecretory plasmacytoid continuous cell line, established for five years in more than 150 passages, is karyotypically normal, easily grown and has the characteristic features of a plasmablast excepting for its secretory defect, and can be used for the preparation of human-human hybridomas with human B-lymphocytes and separation of the resulting hybridomas from the plasmacytoma cell line by growth in CO2-containing media, or by fluorescence activated cell sorting, or both.